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Cidec
Gene Detail
Symbol

Name
ID
Cidec
cell death-inducing DFFA-like effector c
MGI:95585
Synonyms
CIDE-3, CIDE-3alpha, Fsp27
Feature Type
protein coding gene
Genetic Map
Chromosome 6
52.76 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:113424634-113435760 bp, - strand
From VEGA annotation of GRCm38

  11127 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11128  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cidec

Human
homologs
Human Homolog CIDEC, cell death-inducing DFFA-like effector c
NCBI Gene ID 63924
neXtProt AC  NX_Q96AQ7
Human Synonyms  CIDE3, CIDE-3, FPLD5, FSP27
Human Chr (Location)  3p25.3; chr3:9866710-9880257 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CIDEC
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(8) Targeted(5)
 
Nullizygous mice exhibit leaness, high energy expenditure, improved glucose tolerance, altered brown adipocytes, and multilocular fat droplets with enhanced mitochondrial activity and lipolysis in white adipocytes, and may show resistance to age related and diet-induced obesity and liver steatosis.
 
Interactions
Cidec interacts with 107 markers (Mir17, Mir18b, Mir20a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process apoptotic process, execution phase of apoptosis, ...
Component cytosol, endoplasmic reticulum, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (46)    Tissues (45)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 46
cDNA source data(49)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) Genomic(1) cDNA(49) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023130 (Evidence)
Ensembl Gene ModelENSMUSG00000030278 (Evidence)
Entrez Gene14311 (Evidence)
UniGene10026
DFCITC1580634
DoTSDT.101366042, DT.494107
NIA Mouse Gene IndexU041045
PDB4IKG, 4MAC
Consensus CDS ProjectCCDS20418.1
International Mouse Knockout Project StatusCidec
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023130 VEGA Gene Model | MGI Sequence Detail 11127 C57BL/6J ±  kb
transcript OTTMUST00000055899 VEGA | MGI Sequence Detail 785 Not Applicable 
polypeptide OTTMUSP00000026813 VEGA | MGI Sequence Detail 249 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(6) UniProt(5)
Polymorphisms
SNPs within 2kb(83 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003508 Caspase-activated nuclease CIDE-N
Protein Ontology PR:000005494 cell death activator CIDE-3
References
(Earliest) J:154 Danesch U, et al., Cloning and transcriptional regulation of a novel adipocyte-specific gene, FSP27. CAAT-enhancer-binding protein (C/EBP) and C/EBP-like proteins interact with sequences required for differentiation-dependent expression. J Biol Chem. 1992 Apr 5;267(10):7185-93
(Latest) J:209833 Kim J, et al., Peg3 mutational effects on reproduction and placenta-specific gene families. PLoS One. 2013;8(12):e83359
All references(45)
Other
accession IDs
MGD-MRK-9879

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory