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Fbp1
Gene Detail
 Symbol
Name
ID
Fbp1
fructose bisphosphatase 1
MGI:95492
Synonyms Fbp-2, Fbp3, FBPase brain isoform, FBPase liver
Feature Type protein coding gene
Genetic Map
Chromosome 13
32.74 cM, cytoband B3-C1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr13:62864753-62888282 bp, - strand
From VEGA annotation of GRCm38

  23530 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55467  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase
Gene Tree: Fbp1

Human
homologs
Human Homolog FBP1, fructose-1,6-bisphosphatase 1
NCBI Gene ID 2203
neXtProt AC  NX_P09467
Human Synonyms  FBP
Human Chr (Location)  9q22.3; chr9:94603133-94640249 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human FBP1
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Fbp1 interacts with 58 markers (Mir23a, Mir23b, Mir30c-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process carbohydrate metabolic process, cellular response to drug, ...
Component cytoplasm, cytosol, ...
Function AMP binding, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (331)    Tissues (313)    Images (18)
Theiler Stages: 17, 21, 22, 23, 27, 28
Assay TypeResults
RNA in situ 323
RT-PCR 8
cDNA source data(291)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(296) Genomic(3) cDNA(291) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026406 (Evidence)
Ensembl Gene ModelENSMUSG00000069805 (Evidence)
Entrez Gene14121 (Evidence)
UniGene423078
DFCITC1572437
DoTSDT.87069805
NIA Mouse Gene IndexU275872
EC3.1.3.11
Consensus CDS ProjectCCDS26590.1
International Mouse Knockout Project StatusFbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026406 VEGA Gene Model | MGI Sequence Detail 23530 C57BL/6J ±  kb
transcript OTTMUST00000065306 VEGA | MGI Sequence Detail 1479 Not Applicable 
polypeptide OTTMUSP00000032529 VEGA | MGI Sequence Detail 338 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(369 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020548 Fructose-1,6-bisphosphatase, active site
InterPro IPR000146 Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase
Protein Ontology PR:000007365 fructose-1,6-bisphosphatase 1
References (Earliest) J:8049 Nash HR, et al., Fructose bisphosphatase isozymes of the mouse. I. Inheritance. Biochem Genet. 1985 Aug;23(7-8):499-510
(Latest) J:194051 Heliot C, et al., HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85
All references(48)
Other
accession IDs
MGD-MRK-9720, MGD-MRK-9722, MGI:1330236

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory