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Fbp1
Gene Detail
Symbol

Name
ID
Fbp1
fructose bisphosphatase 1
MGI:95492
Synonyms
Fbp-2, Fbp3, FBPase brain isoform, FBPase liver
Feature Type
protein coding gene
Genetic Map
Chromosome 13
32.74 cM, cytoband B3-C1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr13:62864753-62888282 bp, - strand
From VEGA annotation of GRCm38

  23530 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55467  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: FBP1
Protein SuperFamily: fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase
Gene Tree: Fbp1

Human
homologs
FBP1, fructose-1,6-bisphosphatase 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 2203
neXtProt AC: NX_P09467

Human Synonyms: FBP

Human Chr (Location): 9q22.3; chr9:94603133-94640249 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human FBP1

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Fbp1 interacts with 58 markers (Mir23a, Mir23b, Mir30c-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process carbohydrate metabolic process, cellular response to drug, ...
Component cytoplasm, cytosol, ...
Function AMP binding, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (331)    Tissues (313)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 323
RT-PCR 8
cDNA source data(291)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fbp1 ; ZFIN fbp1a    NEW 
Molecular
reagents
All nucleic(296) Genomic(3) cDNA(291) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026406 (Evidence)
Ensembl Gene Model ENSMUSG00000069805 (Evidence)
Entrez Gene 14121 (Evidence)
UniGene 423078
DFCI TC1572437
DoTS DT.87069805
NIA Mouse Gene Index U275872
EC 3.1.3.11
Consensus CDS Project CCDS26590.1
International Mouse Phenotyping Consortium Status Fbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026406 VEGA Gene Model | MGI Sequence Detail 23530 C57BL/6J ±  kb
transcript OTTMUST00000065306 VEGA | MGI Sequence Detail 1479 Not Applicable 
polypeptide OTTMUSP00000032529 VEGA | MGI Sequence Detail 338 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(369 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020548 Fructose-1,6-bisphosphatase, active site
InterPro IPR000146 Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase
Protein Ontology PR:000007365 fructose-1,6-bisphosphatase 1
References
(Earliest) J:8049 Nash HR, et al., Fructose bisphosphatase isozymes of the mouse. I. Inheritance. Biochem Genet. 1985 Aug;23(7-8):499-510
(Latest) J:206636 Nualart F, et al., Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development. Histochem Cell Biol. 2013 Feb;139(2):233-47
All references(47)
Other
accession IDs
MGD-MRK-9720, MGD-MRK-9722, MGI:1330236

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory