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Fbp1 Gene Detail
Summary
  • Symbol
    Fbp1
  • Name
    fructose bisphosphatase 1
  • Synonyms
    Fbp-2, Fbp3, FBPase brain isoform, FBPase liver
  • Feature Type
    protein coding gene
  • IDs
    MGI:95492
    NCBI Gene: 14121
  • Gene Overview
    MyGene.info: FBP1
Location & Maps
more
  • Sequence Map
    Chr13:62864753-62888282 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23530 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 32.74 cM, cytoband B3-C1
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    FBP1, fructose-bisphosphatase 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    FBP1, fructose-bisphosphatase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBP
  • Links
    NCBI Gene ID: 2203
    neXtProt AC: NX_P09467

  • Chr Location
    9q22.32; chr9:94603133-94640249 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human FBP1 associations

Human Disease Mouse Models
       Fructose-1,6-Bisphosphatase Deficiency; FBP1D   OMIM: 229700
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Fbp1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026406 VEGA Gene Model | MGI Sequence Detail 23530 C57BL/6J ±  kb
transcript OTTMUST00000065306 VEGA | MGI Sequence Detail 1479 Not Applicable  
polypeptide OTTMUSP00000032529 VEGA | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    366 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 296
    Genomic 3
    cDNA 291
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-9720, MGD-MRK-9722, MGI:1330236
References
more
  • Summaries
    All 46
    Developmental Gene Expression 15
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:8049 Nash HR, et al., Fructose bisphosphatase isozymes of the mouse. I. Inheritance. Biochem Genet. 1985 Aug;23(7-8):499-510
  • Latest
    J:224441 Lim GE, et al., 14-3-3zeta coordinates adipogenesis of visceral fat. Nat Commun. 2015;6:7671

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory