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Fabp1
Gene Detail
Symbol

Name
ID
Fabp1
fatty acid binding protein 1, liver
MGI:95479
Synonyms
Fabpl, L-FABP, MGC:13855
Feature Type
protein coding gene
Genetic Map
Chromosome 6
32.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr6:71199827-71205023 bp, + strand
From VEGA annotation of GRCm38

  5197 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1106  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FABP1
Protein SuperFamily: lipid binding protein, FABP type
Gene Tree: Fabp1

Human
homologs
FABP1, fatty acid binding protein 1, liver
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2168
neXtProt AC: NX_P07148

Human Synonyms: FABPL, L-FABP

Human Chr (Location): 2p11; chr2:88122982-88128131 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a disruption in this gene do not show any obvious morphological, behavioral, or reproductive abnormalities. Changes may be observed in lipid composition, lipid binding, or levels of lipid binding proteins.
 
Interactions
Fabp1 interacts with 8 markers (Mir302b, Mir302d, Mir325, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (22 records)
Data Summary: Results (6)    Tissues (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 6
cDNA source data(120)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fabp1 ; ZFIN fabp1a, fabp1b.1    NEW 
Molecular
reagents
All nucleic(125) cDNA(122) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000023123 (Evidence)
Ensembl Gene Model ENSMUSG00000054422 (Evidence)
Entrez Gene 14080 (Evidence)
UniGene 22126
DFCI TC1575046
DoTS DT.495164
NIA Mouse Gene Index U007013
Consensus CDS Project CCDS20226.1
International Mouse Phenotyping Consortium Status Fabp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023123 VEGA Gene Model | MGI Sequence Detail 5197 C57BL/6J ±  kb
transcript OTTMUST00000055875 VEGA | MGI Sequence Detail 553 Not Applicable 
polypeptide OTTMUSP00000026804 VEGA | MGI Sequence Detail 127 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(4) : SNPs within 2kb(41 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012674 Calycin
InterPro IPR011038 Calycin-like
InterPro IPR000463 Cytosolic fatty-acid binding
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology PR:000007309 fatty acid-binding protein, liver
References
(Earliest) J:8932 Sweetser DA, et al., The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. J Biol Chem. 1987 Nov 25;262(33):16060-71
(Latest) J:217937 Lin MH, et al., Fatty Acid transport protein 1 can compensate for Fatty Acid transport protein 4 in the developing mouse epidermis. J Invest Dermatol. 2015 Feb;135(2):462-70
All references(92)
Other
accession IDs
MGD-MRK-9706

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory