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Fabp2
Gene Detail
 Symbol
Name
ID
Fabp2
fatty acid binding protein 2, intestinal
MGI:95478
STS D3Mit108
Synonyms Fabpi, Fabpi, I-FABP
Feature Type protein coding gene
Genetic Map
Chromosome 3
53.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr3:122895072-122899506 bp, + strand
From VEGA annotation of GRCm38

  4435 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:107  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: lipid binding protein, FABP type
Gene Tree: Fabp2

Human
homologs
Human Homolog FABP2, fatty acid binding protein 2, intestinal
NCBI Gene ID 2169
neXtProt AC  NX_P12104
Human Synonyms  FABPI, I-FABP
Human Chr (Location)  4q28-q31; chr4:119317250-119322161 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Male mutant mice exhibit increased body weight, hyperinsulinemia, increased leptin levels on a high fat diet and have elevated circulating levels of triglycerides. Female mutant mice exhibit a decreased body weight on a high fat diet compared to controls.
 
Interactions
Fabp2 interacts with 33 markers (Mir7-1, Mir22, Mir139, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process fatty acid metabolic process, intestinal absorption, ...
Component apical cortex, cytoplasm, ...
Function fatty acid binding, lipid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (24 records)
Data Summary: Results (59)    Tissues (55)    Images (5)
Theiler Stages: 11, 13, 15, 21, 23, 25, 26, 28
Assay TypeResults
Immunohistochemistry 2
RT-PCR 57
cDNA source data(64)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(70) Genomic(1) cDNA(66) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000035257 (Evidence)
Ensembl Gene ModelENSMUSG00000023057 (Evidence)
Entrez Gene14079 (Evidence)
UniGene28398
DFCITC1578192, TC1664121
DoTSDT.536663
NIA Mouse Gene IndexU003809
Consensus CDS ProjectCCDS17813.1
International Mouse Knockout Project StatusFabp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035257 VEGA Gene Model | MGI Sequence Detail 4435 C57BL/6J ±  kb
transcript OTTMUST00000089920 VEGA | MGI Sequence Detail 965 Not Applicable 
polypeptide OTTMUSP00000049193 VEGA | MGI Sequence Detail 132 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(57 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012674 Calycin
InterPro IPR011038 Calycin-like
InterPro IPR000463 Cytosolic fatty-acid binding
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology PR:000007310 fatty acid-binding protein, intestinal
References (Earliest) J:7317 Alpers DH, et al., Cloning of a cDNA encoding rat intestinal fatty acid binding protein. Proc Natl Acad Sci U S A. 1984 Jan;81(2):313-7
(Latest) J:208432 Schwarz D, et al., Ezh2 is required for neural crest-derived cartilage and bone formation. Development. 2014 Feb;141(4):867-77
All references(66)
Other
accession IDs
MGD-MRK-9705

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory