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Fabp2
Gene Detail
Symbol

Name
ID
Fabp2
fatty acid binding protein 2, intestinal
MGI:95478
STS
Synonyms
Fabpi, Fabpi, I-FABP
Feature Type
protein coding gene
Genetic Map
Chromosome 3
53.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr3:122895072-122899506 bp, + strand
From VEGA annotation of GRCm38

  4435 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:107  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FABP2
Protein SuperFamily: lipid binding protein, FABP type
Gene Tree: Fabp2

Human
homologs
FABP2, fatty acid binding protein 2, intestinal
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2169
neXtProt AC: NX_P12104

Human Synonyms: FABPI, I-FABP

Human Chr (Location): 4q28-q31; chr4:119317250-119322161 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Male mutant mice exhibit increased body weight, hyperinsulinemia, increased leptin levels on a high fat diet and have elevated circulating levels of triglycerides. Female mutant mice exhibit a decreased body weight on a high fat diet compared to controls.
 
Interactions
Fabp2 interacts with 33 markers (Mir7-1, Mir22, Mir139, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process fatty acid metabolic process, intestinal absorption, ...
Component apical cortex, cytoplasm, ...
Function fatty acid binding, lipid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (25 records)
Data Summary: Results (59)    Tissues (55)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RT-PCR 57
cDNA source data(64)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA FABP2 ; Xenbase fabp2 ; ZFIN fabp2    NEW 
Molecular
reagents
All nucleic(70) Genomic(1) cDNA(66) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000035257 (Evidence)
Ensembl Gene Model ENSMUSG00000023057 (Evidence)
Entrez Gene 14079 (Evidence)
UniGene 28398
DFCI TC1578192, TC1664121
DoTS DT.536663
NIA Mouse Gene Index U003809
Consensus CDS Project CCDS17813.1
International Mouse Phenotyping Consortium Status Fabp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035257 VEGA Gene Model | MGI Sequence Detail 4435 C57BL/6J ±  kb
transcript OTTMUST00000089920 VEGA | MGI Sequence Detail 965 Not Applicable 
polypeptide OTTMUSP00000049193 VEGA | MGI Sequence Detail 132 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(57 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012674 Calycin
InterPro IPR011038 Calycin-like
InterPro IPR000463 Cytosolic fatty-acid binding
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology PR:000007310 fatty acid-binding protein, intestinal
References
(Earliest) J:7317 Alpers DH, et al., Cloning of a cDNA encoding rat intestinal fatty acid binding protein. Proc Natl Acad Sci U S A. 1984 Jan;81(2):313-7
(Latest) J:214986 Walker EM, et al., GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94
All references(66)
Other
accession IDs
MGD-MRK-9705

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory