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Esd Gene Detail
Summary
  • Symbol
    Esd
  • Name
    esterase D/formylglutathione hydrolase
  • Synonyms
    Es10, Es-10, Esd
  • Feature Type
    protein coding gene
  • IDs
    MGI:95421
    NCBI Gene: 13885
  • Gene Overview
    MyGene.info: ESD
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:74732297-74750765 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 39.38 cM, cytoband D2-E2
  • Mapping Data
    44 experiments
Strain
Comparison
more
  • SNPs within 2kb
    285 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95421
protein coding gene Chr14:74732297-74750765 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021563
protein coding gene Chr14:69521036-69544714 (+)
A/J MGP_AJ_G0021521
protein coding gene Chr14:67978125-67996131 (+)
AKR/J MGP_AKRJ_G0021498
protein coding gene Chr14:70003102-70021509 (+)
BALB/cJ MGP_BALBcJ_G0021528
protein coding gene Chr14:67770975-67789563 (+)
C3H/HeJ MGP_C3HHeJ_G0021305
protein coding gene Chr14:69740056-69758466 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021968
protein coding gene Chr14:72567146-72585686 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019506
protein coding gene Chr14:65628212-65647313 (+)
CAST/EiJ MGP_CASTEiJ_G0020822
protein coding gene Chr14:66389344-66407861 (+)
CBA/J MGP_CBAJ_G0021273
protein coding gene Chr14:74903015-74921420 (+)
DBA/2J MGP_DBA2J_G0021396
protein coding gene Chr14:67397358-67416357 (+)
FVB/NJ MGP_FVBNJ_G0021374
protein coding gene Chr14:66725352-66743798 (+)
LP/J MGP_LPJ_G0021466
protein coding gene Chr14:70684973-70706478 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021401
protein coding gene Chr14:73693181-73711650 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021991
protein coding gene Chr14:69283578-69302438 (+)
PWK/PhJ MGP_PWKPhJ_G0020565
protein coding gene Chr14:64125107-64145769 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020401
protein coding gene Chr14:65234293-65252808 (+)
WSB/EiJ MGP_WSBEiJ_G0020875
protein coding gene Chr14:69616787-69638849 (+)



Homology
more
  • Human Ortholog
    ESD, esterase D
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ESD, esterase D
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FGH
  • Links
    NCBI Gene ID: 2098
    neXtProt AC: NX_P10768
    UniProt: P10768

  • Chr Location
    13q14.2; chr13:46771256-46797681 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13885 NCBI Gene Model | MGI Sequence Detail 18469 C57BL/6J ±  kb
transcript NM_001285423 RefSeq | MGI Sequence Detail 2121 C57BL/6  
polypeptide Q9R0P3 UniProt | EBI | MGI Sequence Detail 282 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 236
    cDNA 235
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-9589, MGD-MRK-9622, MGD-MRK-9651
References
more
  • Summaries
    All 83
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:5630 Peters J, et al., Polymorphism of esterase-10 in Mus musculus. Biochem Genet. 1976 Feb;14(1-2):119-25
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory