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Eno3
Gene Detail
Symbol

Name
ID
Eno3
enolase 3, beta muscle
MGI:95395
Synonyms
Eno-3
Feature Type
protein coding gene
Genetic Map
Chromosome 11
43.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr11:70657202-70662513 bp, + strand
From VEGA annotation of GRCm38

  5312 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68215  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: ENO3
Protein SuperFamily: enolase
Gene Tree: Eno3

Human
homologs
ENO3, enolase 3 (beta, muscle)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2027
neXtProt AC: NX_P13929

Human Synonyms: GSD13, MSE

Human Chr (Location): 17p13.2; chr17:4949182-4957131 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ENO3

Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Gene trapped(21) Targeted(3)
Genomic Mutations involving Eno3 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Eno3 interacts with 33 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process glycolytic process
Component cytoplasm, extracellular exosome, ...
Function lyase activity, magnesium ion binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (386)    Tissues (173)    Images (61)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 13
RNA in situ 274
RT-PCR 99
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mgc108129 ; ZFIN eno3    NEW 
Molecular
reagents
All nucleic(16) Genomic(1) cDNA(10) Primer pair(3) Other(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000006071 (Evidence)
Ensembl Gene Model ENSMUSG00000060600 (Evidence)
Entrez Gene 13808 (Evidence)
DFCI TC1575951, TC1646463, TC1677622
DoTS DT.101127363, DT.110532341, DT.495609, DT.55253210, DT.94268036
NIA Mouse Gene Index U012861, U312531
EC 4.2.1.11
Consensus CDS Project CCDS24961.1
International Mouse Phenotyping Consortium Status Eno3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006071 VEGA Gene Model | MGI Sequence Detail 5312 C57BL/6J ±  kb
transcript OTTMUST00000013691 VEGA | MGI Sequence Detail 1454 Not Applicable 
polypeptide OTTMUSP00000006349 VEGA | MGI Sequence Detail 434 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(14) UniProt(6)
Polymorphisms
SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000941 Enolase
InterPro IPR020809 Enolase, conserved site
InterPro IPR020810 Enolase, C-terminal
InterPro IPR020811 Enolase, N-terminal
Protein Ontology PR:000007082 beta-enolase
References
(Earliest) J:9841 Lamande N, et al., Murine muscle-specific enolase: cDNA cloning, sequence, and developmental expression. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4445-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(48)
Other
accession IDs
MGD-MRK-9505, MGD-MRK-9508

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory