Eno1
Gene Detail

Symbol Name ID

Eno1 enolase 1, alpha non-neuron MGI:95393

Synonyms

2-phospho-D-glycerate hydrolase, alpha-enolase, c-Myc promoter binding protein, Eno-1, MBP-1

Feature Type

protein coding gene

Genetic Map

Chromosome 4

81.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)

Sequence Map

Chr4:150236721-150248879 bp, + strand From VEGA annotation of GRCm38   12159 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68183  Vertebrate Homology Class
1 human; 2 mouse; 2 rat; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Eno1

Human homologs

Human Homolog		ENO1, enolase 1, (alpha)
NCBI Gene ID		2023
neXtProt AC		NX_P06733
Human Synonyms		ENO1L1, MPB1, NNE, PPH
Human Chr (Location)		1p36.2; chr1:8921059-8939151 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(82) : Targeted(1) Gene trapped(81)
 

Homozygous animals exhibit growth arrest and embryonic lethality at approximately E6.5.

 

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	cellular response to acid, in utero embryonic development, ...
Component	cytoplasm, extracellular vesicular exosome, ...
Function	phosphopyruvate hydratase activity, protein binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (15 records)
Data Summary: Results (284)    Tissues (161)    Images (56)
Theiler Stages: 14, 15, 17, 18, 19, 20, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	284

cDNA source data(28)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(36) Genomic(1) cDNA(32) Primer pair(1) Other(2)
Microarray probesets(10)

Other database links

VEGA Gene Model	OTTMUSG00000010390 (Evidence)
Ensembl Gene Model	ENSMUSG00000063524 (Evidence)
Entrez Gene	13806 (Evidence)
Consensus CDS Project	CCDS18971.1
International Mouse Knockout Project Status	Eno1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000010390	VEGA Gene Model | MGI Sequence Detail	12159	C57BL/6J
transcript	OTTMUST00000024224	VEGA | MGI Sequence Detail	2027	Not Applicable
polypeptide	OTTMUSP00000011140	VEGA | MGI Sequence Detail	434	Not Applicable

All sequences(142) RefSeq(2)

Polymorphisms

RFLP(2) : SNPs(93 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000007080	alpha-enolase

References

(Earliest) J:5856 D'Ancona GG, et al., Assignment of the gene for enolase to mouse chromosome 4 using somatic cell hybrids. Cytogenet Cell Genet. 1977;19(1):1-6
(Latest) J:172853 Kohr MJ, et al., Characterization of potential S-nitrosylation sites in the myocardium. Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1327-35
All references(68)

Other accession IDs

MGD-MRK-9503, MGD-MRK-9506, MGI:2143710