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Eno1
Gene Detail
Symbol

Name
ID
Eno1
enolase 1, alpha non-neuron
MGI:95393
Synonyms
2-phospho-D-glycerate hydrolase, alpha-enolase, c-Myc promoter binding protein, Eno-1, MBP-1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
81.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr4:150236721-150248879 bp, + strand
From VEGA annotation of GRCm38

  12159 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134343  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ENO1
Gene Tree: Eno1

Human
homologs
ENO1, enolase 1, (alpha)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2023
neXtProt AC: NX_P06733

Human Synonyms: ENO1L1, MPB1, NNE, PPH

Human Chr (Location): 1p36.2; chr1:8861000-8879092 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(83) : Gene trapped(81) Targeted(2)
Genomic Mutations involving Eno1 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous animals exhibit growth arrest and embryonic lethality at approximately E6.5.
 
Interactions
Eno1 interacts with 70 markers (Mir23a, Mir23b, Mir30a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cellular response to acid chemical, in utero embryonic development, ...
Component cytoplasm, extracellular exosome, ...
Function GTPase binding, phosphopyruvate hydratase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (284)    Tissues (162)    Images (56)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 284
cDNA source data(28)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase eno1 ; ZFIN eno1a    NEW 
Molecular
reagents
All nucleic(36) Genomic(1) cDNA(32) Primer pair(1) Other(2)
Microarray probesets(10)
Other database
links
VEGA Gene Model OTTMUSG00000010390 (Evidence)
Ensembl Gene Model ENSMUSG00000063524 (Evidence)
Entrez Gene 13806 (Evidence)
Consensus CDS Project CCDS18971.1
International Mouse Phenotyping Consortium Status Eno1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010390 VEGA Gene Model | MGI Sequence Detail 12159 C57BL/6J ±  kb
transcript OTTMUST00000024224 VEGA | MGI Sequence Detail 2027 Not Applicable 
polypeptide OTTMUSP00000011140 VEGA | MGI Sequence Detail 434 Not Applicable 

For the selected sequences
All sequences(174) RefSeq(6)
Polymorphisms
RFLP(2) : SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000007080 alpha-enolase
References
(Earliest) J:5856 D'Ancona GG, et al., Assignment of the gene for enolase to mouse chromosome 4 using somatic cell hybrids. Cytogenet Cell Genet. 1977;19(1):1-6
(Latest) J:202075 Nakamura N, et al., Disruption of a spermatogenic cell-specific mouse enolase 4 (eno4) gene causes sperm structural defects and male infertility. Biol Reprod. 2013 Apr;88(4):90
All references(64)
Other
accession IDs
MGD-MRK-9503, MGD-MRK-9506, MGI:2143710

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory