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Emb Gene Detail
Summary
  • Symbol
    Emb
  • Name
    embigin
  • Synonyms
    Gp70
  • Feature Type
    protein coding gene
  • IDs
    MGI:95321
    NCBI Gene: 13723
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:117220573-117274415 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 65.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    654 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95321
protein coding gene Chr13:117208536-117274415 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020964
protein coding gene Chr13:120138801-120193778 (+)
A/J MGP_AJ_G0020914
protein coding gene Chr13:115233320-115282725 (+)
AKR/J MGP_AKRJ_G0020889
protein coding gene Chr13:118670827-118724124 (+)
BALB/cJ MGP_BALBcJ_G0020914
protein coding gene Chr13:115958480-116010313 (+)
C3H/HeJ MGP_C3HHeJ_G0020703
protein coding gene Chr13:118513913-118571943 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021350
protein coding gene Chr13:123564240-123615183 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018919
protein coding gene Chr13:110401961-110449407 (+)
CAST/EiJ MGP_CASTEiJ_G0020222
protein coding gene Chr13:118305205-118357876 (+)
CBA/J MGP_CBAJ_G0020665
protein coding gene Chr13:128381589-128437093 (+)
DBA/2J MGP_DBA2J_G0020788
protein coding gene Chr13:114894294-114944458 (+)
FVB/NJ MGP_FVBNJ_G0020772
protein coding gene Chr13:113544159-113598761 (+)
LP/J MGP_LPJ_G0020864
protein coding gene Chr13:120096267-120154929 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020800
protein coding gene Chr13:128749889-128805248 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021386
protein coding gene Chr13:118157171-118217909 (+)
PWK/PhJ MGP_PWKPhJ_G0019975
protein coding gene Chr13:113758148-113807881 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019797
protein coding gene Chr13:114516935-114568837 (+)
WSB/EiJ MGP_WSBEiJ_G0020280
protein coding gene Chr13:118834940-118889404 (+)



Homology
more
  • Human Ortholog
    EMB, embigin
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EMB, embigin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GP70
  • Links
    NCBI Gene ID: 133418
    neXtProt AC: NX_Q6PCB8
    UniProt: Q6PCB8

  • Chr Location
    5q11.1; chr5:50396192-50443299 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7743
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EMB
  • Gene Tree
    Emb
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 13723 NCBI Gene Model | MGI Sequence Detail 53843 C57BL/6J ±  kb
    transcript NM_010330 RefSeq | MGI Sequence Detail 2622 C57BL/6  
    polypeptide P21995 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 37
      cDNA 36
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-10219, MGD-MRK-9364, MGI:2145318, MGI:95795
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 12
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:15311 Ozawa M, et al., A teratocarcinoma glycoprotein carrying a developmentally regulated carbohydrate marker is a member of the immunoglobulin gene superfamily. J Biol Chem. 1988 Mar 5;263(7):3059-62
    • Latest
      J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    last database update
    09/10/2019
    MGI 6.14
    The Jackson Laboratory