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Cela1 Gene Detail
Summary
  • Symbol
    Cela1
  • Name
    chymotrypsin-like elastase family, member 1
  • Synonyms
    1810009A17Rik, 1810062B19Rik, Ela1, Ela-1, PC-TsF
  • Feature Type
    protein coding gene
  • IDs
    MGI:95314
    NCBI Gene: 109901
  • Gene Overview
    MyGene.info: CELA1
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:100674422-100687920 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.38 cM, cytoband F1-F3
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    158 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95314
 protein coding gene Chr15:100674421-100687921 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022359
 protein coding gene Chr15:102658796-102674329 (-)
A/J MGP_AJ_G0022321
 protein coding gene Chr15:98614458-98628469 (-)
AKR/J MGP_AKRJ_G0022297
 protein coding gene Chr15:101625853-101642883 (-)
BALB/cJ MGP_BALBcJ_G0022325
 protein coding gene Chr15:98725093-98739409 (-)
C3H/HeJ MGP_C3HHeJ_G0022095
 protein coding gene Chr15:101707011-101728118 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022773
 protein coding gene Chr15:106515077-106530422 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020298
 protein coding gene Chr15:94364174-94376961 (-)
CAST/EiJ MGP_CASTEiJ_G0021620
 protein coding gene Chr15:102557251-102570764 (-)
CBA/J MGP_CBAJ_G0022064
 protein coding gene Chr15:110159506-110181819 (-)
DBA/2J MGP_DBA2J_G0022191
 protein coding gene Chr15:97965946-97979510 (-)
FVB/NJ MGP_FVBNJ_G0022170
 protein coding gene Chr15:96987867-97004855 (-)
LP/J MGP_LPJ_G0022262
 protein coding gene Chr15:102812836-102828753 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022191
 protein coding gene Chr15:113887693-113904185 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022787
 protein coding gene Chr15:101625813-101646464 (-)
PWK/PhJ MGP_PWKPhJ_G0021359
 protein coding gene Chr15:98098458-98113556 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021191
 protein coding gene Chr15:101520302-101536995 (-)
WSB/EiJ MGP_WSBEiJ_G0021670
 protein coding gene Chr15:102254320-102270812 (-)



Homology
more
  • Human Ortholog
    CELA1, chymotrypsin like elastase 1
  • Vertebrate Orthologs
    14
  • Human Ortholog
    CELA1, chymotrypsin like elastase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ELA1
  • Links
    NCBI Gene ID: 1990
    neXtProt AC: NX_Q9UNI1
    UniProt: Q9UNI1

  • Chr Location
    12q13.13; chr12:51328443-51346679 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Cela1
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    20
  • Tissues
    3
  • cDNA Data
    275
  • Literature Summary
    12
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109901 NCBI Gene Model | MGI Sequence Detail 13499 C57BL/6J ±  kb
transcript NM_033612 RefSeq | MGI Sequence Detail 1124 C57BL/6  
polypeptide Q91X79 UniProt | EBI | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 278
    cDNA 277
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-9350, MGD-MRK-9353, MGI:1917096, MGI:1923996
References
more
  • Summaries
    All 65
    Developmental Gene Expression 12
    Diseases 1
    Gene Ontology 5
    Phenotypes 23
  • Earliest
    J:7529 Honey NK, et al., Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse. Somat Cell Mol Genet. 1984 Jul;10(4):377-83
  • Latest
    J:265607 Naba A, et al., Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep. 2017 Jan 10;7:40495
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/04/2019
MGI 6.14 		The Jackson Laboratory