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Cela1
Gene Detail
Symbol

Name
ID
Cela1
chymotrypsin-like elastase family, member 1
MGI:95314
Synonyms
1810009A17Rik, 1810062B19Rik, Ela1, Ela-1, PC-TsF
Feature Type
protein coding gene
Genetic Map
Chromosome 15
56.38 cM, cytoband F1-F3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr15:100674425-100687920 bp, - strand
From Ensembl annotation of GRCm38

  13496 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20454  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 6 western clawed frog

Protein SuperFamily: trypsin
Gene Tree: Cela1

Human
homologs
Human Homolog CELA1, chymotrypsin-like elastase family, member 1
NCBI Gene ID 1990
neXtProt AC  NX_Q9UNI1
Human Synonyms  ELA1
Human Chr (Location)  12q13; chr12:51328443-51346679 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Radiation induced(1) Targeted(2)
Genomic Mutations involving Cela1 (1)
Interactions
Cela1 interacts with 33 markers (Mir16-1, Mir25, Mir105, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process digestive system development, exocrine pancreas development, ...
Component extracellular region
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (20)    Tissues (3)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 10
Northern blot 8
RT-PCR 2
cDNA source data(274)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(277) cDNA(276) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000023031 (Evidence)
Entrez Gene109901 (Evidence)
UniGene2131
DFCITC1572034, TC1592557
DoTSDT.55134284, DT.55152894
NIA Mouse Gene IndexU041188
EC3.4.21.36
Consensus CDS ProjectCCDS37213.1
International Mouse Knockout Project StatusCela1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023031 Ensembl Gene Model | MGI Sequence Detail 13496 C57BL/6J ±  kb
transcript ENSMUST00000023775 Ensembl | MGI Sequence Detail 1103 Not Applicable 
polypeptide ENSMUSP00000023775 Ensembl | MGI Sequence Detail 266 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(167 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000007008 chymotrypsin-like elastase family member 1
References
(Earliest) J:4779 Honey NK, et al., Assignment in mouse of the genes for chymotrypsinogen B, elastase, trypsin, and carboxypeptidase A (Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983) Seventh International Workshop on Human Gene Mapping). Cytogenet Cell Genet. 1984;37 (1-4):492-493 (Abstr.) (399-616)
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(47)
Other
accession IDs
MGD-MRK-9350, MGD-MRK-9353, MGI:1917096, MGI:1923996

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory