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Eif3a
Gene Detail
Symbol

Name
ID
Eif3a
eukaryotic translation initiation factor 3, subunit A
MGI:95301
Synonyms
A830012B05Rik, Csma, Eif3, Eif3s10
Feature Type
protein coding gene
Genetic Map
Chromosome 19
56.52 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:60761116-60790693 bp, - strand
From NCBI annotation of GRCm38

  29578 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2779  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: EIF3A
Gene Tree: Eif3a

Human
homologs
EIF3A, eukaryotic translation initiation factor 3, subunit A
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8661
neXtProt AC: NX_Q14152

Human Synonyms: EIF3, eIF3-p170, EIF3S10, eIF3-theta, P167, p180, p185, TIF32

Human Chr (Location): 10q26; chr10:119035029-119080822 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(40) : Gene trapped(38) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Eif3a interacts with 243 markers (Mir7-1, Mir10a, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process formation of cytoplasmic translation initiation complex, translation, ...
Component cytoplasm, cytoskeleton, ...
Function poly(A) RNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (42)    Tissues (28)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 42
cDNA source data(22)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase eif3a    NEW 
Molecular
reagents
All nucleic(23) Genomic(1) cDNA(22)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000024991 (Evidence)
Entrez Gene 13669 (Evidence)
DFCI TC1573978, TC1598423, TC1615454
Consensus CDS Project CCDS38035.1
International Mouse Phenotyping Consortium Status Eif3a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 13669 NCBI Gene Model | MGI Sequence Detail 29578 C57BL/6J ±  kb
transcript NM_010123 RefSeq | MGI Sequence Detail 5176 C57BL/6 
polypeptide P23116 UniProt | EBI | MGI Sequence Detail 1344 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(193 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027512 Eukaryotic translation initiation factor 3 subunit A
InterPro IPR000717 Proteasome component (PCI) domain
Protein Ontology PR:000006973 eukaryotic translation initiation factor 3 subunit A
Graphical View of Protein Domain Structure
References
(Earliest) J:11284 Joswig G, et al., Murine cDNAs coding for the centrosomal antigen centrosomin A. J Cell Sci. 1991 Jan;98(Pt 1):37-43
(Latest) J:216392 Kraushar ML, et al., Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3815-24
All references(41)
Other
accession IDs
MGD-MRK-2196, MGD-MRK-9334, MGI:2443799, MGI:88538

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory