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Eif3a
Gene Detail
 Symbol
Name
ID
Eif3a
eukaryotic translation initiation factor 3, subunit A
MGI:95301
Synonyms A830012B05Rik, Csma, Eif3, Eif3s10
Feature Type protein coding gene
Genetic Map
Chromosome 19
56.52 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:60761116-60790693 bp, - strand
From NCBI annotation of GRCm38

  29578 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2779  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Eif3a

Human
homologs
Human Homolog EIF3A, eukaryotic translation initiation factor 3, subunit A
NCBI Gene ID 8661
neXtProt AC  NX_Q14152
Human Synonyms  EIF3, eIF3-p170, EIF3S10, eIF3-theta, P167, p180, p185, TIF32
Human Chr (Location)  10q26; chr10:119035029-119080822 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(40) : Gene trapped(38) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Eif3a interacts with 244 markers (Mir7-1, Mir10a, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process formation of translation initiation complex, translation, ...
Component cytoplasm, cytoskeleton, ...
Function poly(A) RNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (42)    Tissues (28)    Images (13)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 42
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(1) cDNA(22)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000024991 (Evidence)
Entrez Gene13669 (Evidence)
DFCITC1573978, TC1598423, TC1615454
Consensus CDS ProjectCCDS38035.1
International Mouse Knockout Project StatusEif3a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 13669 NCBI Gene Model | MGI Sequence Detail 29578 C57BL/6J ±  kb
transcript NM_010123 RefSeq | MGI Sequence Detail 5176 C57BL/6 
polypeptide P23116 UniProt | EBI | MGI Sequence Detail 1344 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(7)
Polymorphisms SNPs within 2kb(193 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027512 Eukaryotic translation initiation factor 3 subunit A
InterPro IPR000717 Proteasome component (PCI) domain
Protein Ontology PR:000006973 eukaryotic translation initiation factor 3 subunit A
Graphical View of Protein Domain Structure
References (Earliest) J:11284 Joswig G, et al., Murine cDNAs coding for the centrosomal antigen centrosomin A. J Cell Sci. 1991 Jan;98(Pt 1):37-43
(Latest) J:204915 Zeng L, et al., The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control. J Biol Chem. 2013 Oct 18;288(42):30087-93
All references(42)
Other
accession IDs
MGD-MRK-2196, MGD-MRK-9334, MGI:2443799, MGI:88538

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory