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Klk1b9
Gene Detail
 Symbol
Name
ID
Klk1b9
kallikrein 1-related peptidase b9
MGI:95293
Synonyms Egfbp3, Egfbp-3, Klk9, mGk-9
Feature Type protein coding gene
Genetic Map
Chromosome 7
28.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr7:43976061-43980376 bp, + strand
From VEGA annotation of GRCm38

  4316 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Klk1b9

Human
homologs
Human Homolog KLK3, kallikrein-related peptidase 3
NCBI Gene ID 354
neXtProt AC  NX_P07288
Human Synonyms  APS, hK3, KLK2A1, PSA
Human Chr (Location)  19q13.41; chr19:50854915-50860764 (+)  GRCh38
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klk1b9 interacts with 13 markers (Mir92-1, Mir153, Mir183, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process proteolysis, zymogen activation
Component extracellular vesicular exosome, nucleus
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (36)    Tissues (9)   
Theiler Stages: 1, 2, 4, 11, 15, 18, 28
Assay TypeResults
RT-PCR 36
cDNA source data(26)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(36) Genomic(9) cDNA(26) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000027239 (Evidence)
Ensembl Gene ModelENSMUSG00000059042 (Evidence)
Entrez Gene13648 (Evidence)
UniGene440884
DFCITC1586031
NIA Mouse Gene IndexU167068
EC3.4.21.35
Consensus CDS ProjectCCDS21191.1
International Mouse Knockout Project StatusKlk1b9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027239 VEGA Gene Model | MGI Sequence Detail 4316 C57BL/6J ±  kb
transcript OTTMUST00000067358 VEGA | MGI Sequence Detail 870 Not Applicable 
polypeptide OTTMUSP00000033878 VEGA | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(1)
Polymorphisms RFLP(2) : SNPs within 2kb(124 from dbSNP Build 137)    SNPs within 2kb including multiple locations(136)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009615 kallikrein 1-related peptidase b9
References (Earliest) J:8756 Evans BA, et al., Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus. J Biol Chem. 1987 Jun 15;262(17):8027-34
(Latest) J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41
All references(34)
Other
accession IDs
MGD-MRK-9318, MGD-MRK-9321

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory