About   Help   FAQ
Eed Gene Detail
Summary
  • Symbol
    Eed
  • Name
    embryonic ectoderm development
  • Synonyms
    l(7)5Rn, l7Rn5
  • Feature Type
    protein coding gene
  • IDs
    MGI:95286
    NCBI Gene: 13626
Location & Maps
more
  • Sequence Map
    Chr7:89954656-89980983 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26328 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    EED, embryonic ectoderm development
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EED, embryonic ectoderm development
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HEED, WAIT1
  • Links
    NCBI Gene ID: 8726
    neXtProt AC: NX_O75530

  • Chr Location
    11q14.2-q22.3; chr11:86244544-86285420 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2814
    1 human;1 mouse;1 rat;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: EED
  • Gene Tree
    Eed
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    58 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    125
  • Chemically induced (ENU)
    4
  • Chemically induced (other)
    1
  • Gene trapped
    113
  • Radiation induced
    3
  • Targeted
    4
  • Genomic Mutations
    4 involving Eed
  • Incidental Mutations
Homozygous mutant mice are dwarfed and their coat color is dilute.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021134 VEGA Gene Model | MGI Sequence Detail 26328 C57BL/6J ±  kb
transcript OTTMUST00000050031 VEGA | MGI Sequence Detail 2065 Not Applicable  
polypeptide OTTMUSP00000023294 VEGA | MGI Sequence Detail 441 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    215 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 106
    Genomic 4
    cDNA 92
    Primer pair 1
    Other 9

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11693, MGD-MRK-11725, MGD-MRK-9305, MGI:3584396, MGI:3641985, MGI:96737
References
more
  • Summaries
    All 121
    Developmental Gene Expression 27
    Gene Ontology 24
    Phenotypes 58
  • Earliest
    J:2961 Sharan SK, et al., The albino-deletion complex of the mouse: molecular mapping of deletion breakpoints that define regions necessary for development of the embryonic and extraembryonic ectoderm. Genetics. 1991 Nov;129(3):825-32
  • Latest
    J:218057 Zheng HJ, et al., The Novel Helicase helG (DHX30) Is Expressed During Gastrulation in Mice and Has a Structure Similar to a Human DExH Box Helicase. Stem Cells Dev. 2015 Feb 1;24(3):372-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory