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Dpep1 Gene Detail
Summary
  • Symbol
    Dpep1
  • Name
    dipeptidase 1 (renal)
  • Synonyms
    MBD
  • Feature Type
    protein coding gene
  • IDs
    MGI:94917
    NCBI Gene: 13479
  • Gene Overview
    MyGene.info: DPEP1
Location & Maps
more
  • Sequence Map
    Chr8:123186235-123201810 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15576 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 72.08 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    DPEP1, dipeptidase 1 (renal)
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DPEP1, dipeptidase 1 (renal)
    Orthology source: HomoloGene
  • Synonyms
    MBD1, MDP, RDP
  • Links
    NCBI Gene ID: 1800
    neXtProt AC: NX_P16444

  • Chr Location
    16q24.3; chr16:89613308-89640862 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Mice homozygous for disruption of this gene ar phenotypically normal although defects have been noted in the conversion of leukotriene D4 to leukotrience E4.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019278 Ensembl Gene Model | MGI Sequence Detail 15576 C57BL/6J ±  kb
transcript ENSMUST00000019422 Ensembl | MGI Sequence Detail 2241 Not Applicable  
polypeptide ENSMUSP00000019422 Ensembl | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    324 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-8882, MGI:2142515
References
more
  • Summaries
    All 32
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:12584 Satoh S, et al., Purification and molecular cloning of mouse renal dipeptidase. Biochim Biophys Acta. 1993 Jun 4;1163(3):234-42
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory