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Dmwd Gene Detail
Summary
  • Symbol
    Dmwd
  • Name
    dystrophia myotonica-containing WD repeat motif
  • Synonyms
    59, Dm9, DMR-N9
  • Feature Type
    protein coding gene
  • IDs
    MGI:94907
    NCBI Gene: 13401
  • Gene Overview
    MyGene.info: DMWD
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:19076227-19082776 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.46 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    44 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_94907
protein coding gene Chr7:19076090-19082778 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031756
protein coding gene Chr7:17027104-17035919 (+)
A/J MGP_AJ_G0031732
protein coding gene Chr7:16716487-16723031 (+)
AKR/J MGP_AKRJ_G0031658
protein coding gene Chr7:17175470-17182014 (+)
BALB/cJ MGP_BALBcJ_G0031737
protein coding gene Chr7:16909196-16916130 (+)
C3H/HeJ MGP_C3HHeJ_G0031459
protein coding gene Chr7:17434472-17441000 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032203
protein coding gene Chr7:17919693-17926242 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029269
protein coding gene Chr7:18364768-18371530 (+)
CAST/EiJ MGP_CASTEiJ_G0030802
protein coding gene Chr7:13835373-13843503 (+)
CBA/J MGP_CBAJ_G0031421
protein coding gene Chr7:18562990-18569539 (+)
DBA/2J MGP_DBA2J_G0031576
protein coding gene Chr7:16651847-16658706 (+)
FVB/NJ MGP_FVBNJ_G0031528
protein coding gene Chr7:16515663-16522622 (+)
LP/J MGP_LPJ_G0031659
protein coding gene Chr7:17372480-17379029 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031564
protein coding gene Chr7:18431332-18437912 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032231
protein coding gene Chr7:16780942-16788865 (+)
PWK/PhJ MGP_PWKPhJ_G0030526
protein coding gene Chr7:13740204-13746786 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030353
protein coding gene Chr7:11465592-11472740 (+)
WSB/EiJ MGP_WSBEiJ_G0030902
protein coding gene Chr7:16981747-16990136 (+)



Homology
more
  • Human Ortholog
    DMWD, DM1 locus, WD repeat containing
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DMWD, DM1 locus, WD repeat containing
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D19S593E, DMRN9, DMR-N9, gene59
  • Links
    NCBI Gene ID: 1762
    neXtProt AC: NX_Q09019
    UniProt: Q09019

  • Chr Location
    19q13.32; chr19:45783006-45792802 (-)  GRCh38.p7

Human Diseases
less
  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotypes from multigenic genotypes
    23 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030410 Ensembl Gene Model | MGI Sequence Detail 6550 C57BL/6J ±  kb
transcript ENSMUST00000032570 Ensembl | MGI Sequence Detail 2494 Not Applicable  
polypeptide ENSMUSP00000032570 Ensembl | MGI Sequence Detail 665 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 83
    Genomic 6
    cDNA 77

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-8867
References
more
  • Summaries
    All 49
    Developmental Gene Expression 1
    Diseases 2
    Gene Ontology 1
    Phenotypes 23
  • Earliest
    J:12705 Jansen G, et al., Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs. Nat Genet. 1992 Jul;1(4):261-6
  • Latest
    J:254355 Sicot G, et al., Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy. Cell Rep. 2017 Jun 27;19(13):2718-2729

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory