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Cyb5r3 Gene Detail
Summary
  • Symbol
    Cyb5r3
  • Name
    cytochrome b5 reductase 3
  • Synonyms
    0610016L08Rik, 2500002N19Rik, Dia1, Dia-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:94893
    NCBI Gene: 109754
  • Gene Overview
    MyGene.info: CYB5R3
  • Alliance
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:83153495-83172208 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 39.40 cM, cytoband E
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    155 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_94893
protein coding gene Chr15:83153494-83172592 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022160
protein coding gene Chr15:83819428-83837858 (-)
A/J MGP_AJ_G0022119
protein coding gene Chr15:80767604-80788916 (-)
AKR/J MGP_AKRJ_G0022094
protein coding gene Chr15:83082512-83102898 (-)
BALB/cJ MGP_BALBcJ_G0022125
protein coding gene Chr15:80912275-80931196 (-)
C3H/HeJ MGP_C3HHeJ_G0021895
protein coding gene Chr15:83079782-83101483 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022570
protein coding gene Chr15:87056652-87080216 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020094
protein coding gene Chr15:77152435-77170771 (-)
CAST/EiJ MGP_CASTEiJ_G0021417
protein coding gene Chr15:83814408-83845898 (-)
CBA/J MGP_CBAJ_G0021862
protein coding gene Chr15:89804303-89829876 (-)
DBA/2J MGP_DBA2J_G0021989
protein coding gene Chr15:80260082-80279231 (-)
FVB/NJ MGP_FVBNJ_G0021968
protein coding gene Chr15:79296289-79318551 (-)
LP/J MGP_LPJ_G0022060
protein coding gene Chr15:83994035-84014979 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021988
protein coding gene Chr15:94732805-94762181 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022585
protein coding gene Chr15:83127217-83146572 (-)
PWK/PhJ MGP_PWKPhJ_G0021158
protein coding gene Chr15:80235687-80255420 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020992
protein coding gene Chr15:82842579-82861066 (-)
WSB/EiJ MGP_WSBEiJ_G0021466
protein coding gene Chr15:83616390-83636816 (-)



Homology
more
  • Human Ortholog
    CYB5R3, cytochrome b5 reductase 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CYB5R3, cytochrome b5 reductase 3
    Orthology source: HGNC
  • Synonyms
    B5R, DIA1
  • Links
    NCBI Gene ID: 1727
    neXtProt AC: NX_P00387
    UniProt: P00387

  • Chr Location
    22q13.2; chr22:42617840-42649399 (-)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 109754 NCBI Gene Model | MGI Sequence Detail 18714 C57BL/6J ±  kb
transcript NM_029787 RefSeq | MGI Sequence Detail 2028 C57BL/6  
polypeptide Q9DCN2 UniProt | EBI | MGI Sequence Detail 301 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006082 NADH-cytochrome b5 reductase 3
  • EC
  • InterPro Domains
    IPR017927 FAD-binding domain, ferredoxin reductase-type
    IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
    IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase
    IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain
    IPR001834 NADH:cytochrome b5 reductase (CBR)
    IPR001433 Oxidoreductase FAD/NAD(P)-binding
    IPR017938 Riboflavin synthase-like beta-barrel
Molecular
Reagents
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  • All nucleic 239
    cDNA 237
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-8844, MGD-MRK-8846, MGI:1919569, MGI:1924141, MGI:2146303
References
more
  • Summaries
    All 69
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 8
    Phenotypes 25
  • Earliest
    J:6442 Taggart RT, et al., Assignment of the gene for NADH diaphorase Dia-1 to Mouse chromosome 15. Somatic Cell Genet. 1980 Nov;6(6):769-76
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory