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Cyb5r3 Gene Detail
Summary
  • Symbol
    Cyb5r3
  • Name
    cytochrome b5 reductase 3
  • Synonyms
    0610016L08Rik, 2500002N19Rik, Dia1, Dia-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:94893
    NCBI Gene: 109754
Location & Maps
more
  • Sequence Map
    Chr15:83153494-83172592 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19099 bp   ±  kb flank

  • Genome Browsers
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    1
  • Gene trapped
    12
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Cyb5r3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030694 VEGA Gene Model | MGI Sequence Detail 19099 C57BL/6J ±  kb
transcript OTTMUST00000075995 VEGA | MGI Sequence Detail 2547 Not Applicable  
polypeptide OTTMUSP00000039933 VEGA | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    159 from dbSNP Build 137
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006082 NADH-cytochrome b5 reductase 3
  • EC
  • InterPro Domains
    IPR017927 Ferredoxin reductase-type FAD-binding domain
    IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase
    IPR001834 NADH:cytochrome b5 reductase (CBR)
    IPR008333 Oxidoreductase, FAD-binding domain
    IPR001433 Oxidoreductase FAD/NAD(P)-binding
    IPR017938 Riboflavin synthase-like beta-barrel
Molecular
Reagents
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  • All nucleic 238
    cDNA 236
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-8844, MGD-MRK-8846, MGI:1919569, MGI:1924141, MGI:2146303
References
more
  • Summaries
    All 45
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 6
    Phenotypes 24
  • Earliest
    J:6442 Taggart RT, et al., Assignment of the gene for NADH diaphorase Dia-1 to Mouse chromosome 15. Somatic Cell Genet. 1980 Nov;6(6):769-76
  • Latest
    J:221087 Jakobs HH, et al., The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice. PLoS One. 2014;9(8):e105371

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory