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Dbp
Gene Detail
 Symbol
Name
ID
Dbp
D site albumin promoter binding protein
MGI:94866
Feature Type protein coding gene
Genetic Map
Chromosome 7
29.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:45705088-45710155 bp, + strand
From VEGA annotation of GRCm38

  5068 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1035  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Dbp

Human
homologs
Human Homolog DBP, D site of albumin promoter (albumin D-box) binding protein
NCBI Gene ID 1628
neXtProt AC  NX_Q10586
Human Synonyms  DABP
Human Chr (Location)  19q13.3; chr19:48630560-48637382 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(12) Targeted(3)
 
Mice homozygous for a null mutation display a shortened circadian period and decreased acvtivity during the dark phase.
 
Interactions
Dbp interacts with 34 markers (Mir20a, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process circadian rhythm, positive regulation of transcription from RNA polymerase II promoter, ...
Component nucleus
Function DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (229)    Tissues (122)    Images (21)
Theiler Stages: 15, 17, 19, 22, 23, 24, 26, 28
Assay TypeResults
RNA in situ 229
cDNA source data(8)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) Genomic(2) cDNA(9) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023187 (Evidence)
Ensembl Gene ModelENSMUSG00000059824 (Evidence)
Entrez Gene13170 (Evidence)
Consensus CDS ProjectCCDS21260.1
International Mouse Knockout Project StatusDbp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023187 VEGA Gene Model | MGI Sequence Detail 5068 C57BL/6J ±  kb
transcript OTTMUST00000056095 VEGA | MGI Sequence Detail 1789 Not Applicable 
polypeptide OTTMUSP00000026915 VEGA | MGI Sequence Detail 325 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(6) UniProt(5)
Polymorphisms RFLP(1) : SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
Protein Ontology PR:000006298 D site-binding protein
References (Earliest) J:909 Szpirer C, et al., Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF). Genomics. 1992 Jun;13(2):293-300
(Latest) J:186817 Bein K, et al., JUN-CCAAT/enhancer-binding protein complexes inhibit surfactant-associated protein B promoter activity. Am J Respir Cell Mol Biol. 2011 Aug;45(2):436-44
All references(53)
Other
accession IDs
MGD-MRK-8803

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory