Dbp
Gene Detail

Symbol

Name
ID

Dbp
D site albumin promoter binding protein
MGI:94866

Feature Type

protein coding gene

Genetic Map

Chromosome 7
29.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:45705088-45710155 bp, + strand From VEGA annotation of GRCm38   5068 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:1035  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Gene Tree: Dbp

Human
homologs

Human Homolog		DBP, D site of albumin promoter (albumin D-box) binding protein
NCBI Gene ID		1628
neXtProt AC		NX_Q10586
Human Synonyms		DABP
Human Chr (Location)		19q13.3; chr19:48630560-48637382 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(15) : Gene trapped(12) Targeted(3)
 

Mice homozygous for a null mutation display a shortened circadian period and decreased acvtivity during the dark phase.

 

Interactions

Dbp interacts with 34 markers (Mir20a, Mir22, Mir23a, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (14 annotations)

Process	circadian rhythm, positive regulation of transcription from RNA polymerase II promoter, ...
Component	nucleus
Function	DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, ...

External Resources: FuncBase

Expression

Literature Summary: (8 records)

Data Summary: Results (229)    Tissues (123)    Images (21)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	229

cDNA source data(8)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas

Molecular
reagents

All nucleic(12) Genomic(2) cDNA(9) Primer pair(1)
Microarray probesets(4)

Other database
links

VEGA Gene Model	OTTMUSG00000023187 (Evidence)
Ensembl Gene Model	ENSMUSG00000059824 (Evidence)
Entrez Gene	13170 (Evidence)
Consensus CDS Project	CCDS21260.1
International Mouse Knockout Project Status	Dbp

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023187	VEGA Gene Model | MGI Sequence Detail	5068	C57BL/6J
transcript	OTTMUST00000056095	VEGA | MGI Sequence Detail	1789	Not Applicable
polypeptide	OTTMUSP00000026915	VEGA | MGI Sequence Detail	325	Not Applicable

All sequences(47) RefSeq(6) UniProt(9)

Polymorphisms

RFLP(1) : SNPs within 2kb(40 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR004827	Basic-leucine zipper domain
Protein Ontology	PR:000006298	D site-binding protein

References

(Earliest) J:909 Szpirer C, et al., Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF). Genomics. 1992 Jun;13(2):293-300
(Latest) J:186817 Bein K, et al., JUN-CCAAT/enhancer-binding protein complexes inhibit surfactant-associated protein B promoter activity. Am J Respir Cell Mol Biol. 2011 Aug;45(2):436-44
All references(53)

Other
accession IDs

MGD-MRK-8803