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Dbp Gene Detail
Summary
  • Symbol
    Dbp
  • Name
    D site albumin promoter binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:94866
    NCBI Gene: 13170
  • Gene Overview
    MyGene.info: DBP
Location & Maps
more
  • Sequence Map
    Chr7:45705088-45710203 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      5116 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.45 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    DBP, D-box binding PAR bZIP transcription factor
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DBP, D-box binding PAR bZIP transcription factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DABP
  • Links
    NCBI Gene ID: 1628
    neXtProt AC: NX_Q10586

  • Chr Location
    19q13.3; chr19:48630560-48637550 (-)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 1035
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 frog, western clawed
  • HCOP
    human homology predictions: DBP
  • Gene Tree
    Dbp
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotypes from multigenic genotypes
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    15
  • Gene trapped
    12
  • Targeted
    3
  • Incidental Mutations
    CvDC
Mice homozygous for a null mutation display a shortened circadian period and decreased acvtivity during the dark phase.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    229
  • Tissues
    123
  • cDNA Data
    8
  • Literature Summary
    8
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023187 VEGA Gene Model | MGI Sequence Detail 5116 C57BL/6J ±  kb
transcript OTTMUST00000056095 VEGA | MGI Sequence Detail 1837 Not Applicable  
polypeptide OTTMUSP00000026915 VEGA | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    41 from dbSNP Build 142
  • RFLP
    1
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006298 D site-binding protein
  • InterPro Domains
    IPR004827 Basic-leucine zipper domain
    IPR029830 D site-binding protein
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 9
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-8803
References
more
  • Summaries
    All 53
    Developmental Gene Expression 8
    Gene Ontology 6
    Phenotypes 16
  • Earliest
    J:909 Szpirer C, et al., Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF). Genomics. 1992 Jun;13(2):293-300
  • Latest
    J:186817 Bein K, et al., JUN-CCAAT/enhancer-binding protein complexes inhibit surfactant-associated protein B promoter activity. Am J Respir Cell Mol Biol. 2011 Aug;45(2):436-44
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory