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Dcaf11 Gene Detail
Summary
  • Symbol
    Dcaf11
  • Name
    DDB1 and CUL4 associated factor 11
  • Synonyms
    0710008A13Rik, D14Ucla1, GLO14, Wdr23
  • Feature Type
    protein coding gene
  • IDs
    MGI:90168
    NCBI Gene: 28199
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55560006-55570065 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    109 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_90168
 protein coding gene Chr14:55559125-55570065 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021349
 protein coding gene Chr14:49593338-49603397 (+)
A/J MGP_AJ_G0021308
 protein coding gene Chr14:48606162-48616221 (+)
AKR/J MGP_AKRJ_G0021284
 protein coding gene Chr14:50352505-50362564 (+)
BALB/cJ MGP_BALBcJ_G0021312
 protein coding gene Chr14:48552855-48562914 (+)
C3H/HeJ MGP_C3HHeJ_G0021092
 protein coding gene Chr14:50039107-50049166 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021750
 protein coding gene Chr14:52087339-52097398 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019297
 protein coding gene Chr14:46979426-46989471 (+)
CAST/EiJ MGP_CASTEiJ_G0020611
 protein coding gene Chr14:46302566-46312575 (+)
CBA/J MGP_CBAJ_G0021059
 protein coding gene Chr14:53644853-53654912 (+)
DBA/2J MGP_DBA2J_G0021180
 protein coding gene Chr14:48332050-48342109 (+)
FVB/NJ MGP_FVBNJ_G0021162
 protein coding gene Chr14:47781048-47791118 (+)
LP/J MGP_LPJ_G0021254
 protein coding gene Chr14:50639553-50649612 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021186
 protein coding gene Chr14:53004369-53014439 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021777
 protein coding gene Chr14:49539950-49550009 (+)
PWK/PhJ MGP_PWKPhJ_G0020358
 protein coding gene Chr14:44862372-44872431 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020186
 protein coding gene Chr14:45537819-45547830 (+)
WSB/EiJ MGP_WSBEiJ_G0020664
 protein coding gene Chr14:49823366-49833437 (+)



Homology
more
  • Human Ortholog
    DCAF11, DDB1 and CUL4 associated factor 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DCAF11, DDB1 and CUL4 associated factor 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GL014, PRO2389, WDR23
  • Links
    NCBI Gene ID: 80344
    neXtProt AC: NX_Q8TEB1
    UniProt: Q8TEB1

  • Chr Location
    14q12; chr14:24114697-24125242 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    11
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022214 Ensembl Gene Model | MGI Sequence Detail 10060 C57BL/6J ±  kb
transcript ENSMUST00000128490 Ensembl | MGI Sequence Detail 2660 Not Applicable  
polypeptide ENSMUSP00000114211 Ensembl | MGI Sequence Detail 549 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-3966, MGI:1918950, MGI:2145858
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
  • Latest
    J:266543 Zhang YL, et al., DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development. EMBO J. 2018 Sep 14;37(18)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/03/2019
MGI 6.14 		The Jackson Laboratory