About   Help   FAQ
Take the Alliance for Genomic Resources User Survey
Dcaf11 Gene Detail
Summary
  • Symbol
    Dcaf11
  • Name
    DDB1 and CUL4 associated factor 11
  • Synonyms
    0710008A13Rik, D14Ucla1, GLO14, Wdr23
  • Feature Type
    protein coding gene
  • IDs
    MGI:90168
    NCBI Gene: 28199
Location & Maps
more
  • Sequence Map
    Chr14:55560006-55570065 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      10060 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    DCAF11, DDB1 and CUL4 associated factor 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DCAF11, DDB1 and CUL4 associated factor 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GL014, PRO2389, WDR23
  • Links
    NCBI Gene ID: 80344
    neXtProt AC: NX_Q8TEB1

  • Chr Location
    14q11.2; chr14:24114697-24125242 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    4
  • Genomic Mutations
    1 involving Dcaf11
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    10
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027921 VEGA Gene Model | MGI Sequence Detail 10060 C57BL/6J ±  kb
transcript OTTMUST00000069150 VEGA | MGI Sequence Detail 2538 Not Applicable  
polypeptide OTTMUSP00000035082 VEGA | MGI Sequence Detail 549 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    109 from dbSNP Build 142
  • RFLP
    1
Protein
Information
less
  • UniProt
    11 Sequences
  • Protein Ontology
    PR:000031241 DDB1- and CUL4-associated factor 11
  • InterPro Domains
    IPR020472 G-protein beta WD-40 repeat
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
    IPR017399 WD repeat protein DCAF11/LEC14B
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-3966, MGI:1918950, MGI:2145858
References
more
  • Summaries
    All 33
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory