Uty
Gene Detail

Symbol Name ID

Uty ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome MGI:894810

Synonyms

Hydb

Feature Type

protein coding gene

Genetic Map

Chromosome Y
Syntenic

Mapping data(5)

Sequence Map

ChrY:1096861-1245759 bp, - strand From VEGA annotation of GRCm38   148899 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Gene Tree: Uty

Alleles and phenotypes

All alleles(13) : Gene trapped(13)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	canonical Wnt receptor signaling pathway, cardiac muscle cell contraction, ...
Component	nucleus
Function	histone demethylase activity (H3-K36 specific), metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (7 records)
Data Summary: Results (67)    Tissues (44)    Images (2)
Theiler Stages: 2, 3, 4, 5, 19, 21, 23, 28

Assay Type	Results
RNA in situ	24
RT-PCR	43

cDNA source data(37)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(46) Genomic(5) cDNA(37) Primer pair(3) Other(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000032814 (Evidence)
Ensembl Gene Model	ENSMUSG00000068457 (Evidence)
Entrez Gene	22290 (Evidence)
UniGene	20477
DFCI	TC1583039, TC1593802, TC1715621
DoTS	DT.101340593, DT.101375407, DT.110950138, DT.55180876, DT.87035494, DT.97360318
NIA Mouse Gene Index	U081436
EC	1.14.11.-
Consensus CDS Project	CCDS41216.1
International Mouse Knockout Project Status	Uty

Sequences

Length	Strain/Species
genomic	OTTMUSG00000032814	VEGA Gene Model | MGI Sequence Detail	148899	C57BL/6J
transcript	OTTMUST00000081742	VEGA | MGI Sequence Detail	5208	Not Applicable
polypeptide	OTTMUSP00000043769	VEGA | MGI Sequence Detail	1212	Not Applicable

All sequences(79) RefSeq(2) UniProt(13)

Polymorphisms

SNPs(80 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003347	JmjC domain
InterPro	IPR011990	Tetratricopeptide-like helical
InterPro	IPR019734	Tetratricopeptide repeat
InterPro	IPR013026	Tetratricopeptide repeat-containing domain
InterPro	IPR001440	Tetratricopeptide TPR-1
InterPro	IPR013105	Tetratricopeptide TPR2
Protein Ontology	PR:000017213	histone demethylase UTY

References

(Earliest) J:21470 King TR, et al., Deletion mapping by immunoselection against the H-Y histocompatibility antigen further resolves the Sxra region of the mouse Y chromosome and reveals complexity of the Hya locus. Genomics. 1994 Nov 1;24(1):159-68
(Latest) J:190157 Wang C, et al., UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15324-9
All references(37)

Other accession IDs

MGD-MRK-11034, MGI:96299