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Uty
Gene Detail
 Symbol
Name
ID
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
MGI:894810
Synonyms Hydb
Feature Type protein coding gene
Genetic Map
Chromosome Y
Syntenic

Mapping data(5)
Sequence Map
ChrY:1096861-1245759 bp, - strand
From VEGA annotation of GRCm38

  148899 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Uty
Alleles
and
phenotypes
All alleles(13) : Gene trapped(13)
 
Mutant male mice hemizygous for a gene trapped allele are viable and fertile.
 
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process canonical Wnt signaling pathway, cardiac muscle cell contraction, ...
Component nucleus
Function dioxygenase activity, histone demethylase activity (H3-K36 specific), ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (67)    Tissues (44)    Images (2)
Theiler Stages: 2, 3, 4, 5, 19, 21, 23, 28
Assay TypeResults
RNA in situ 24
RT-PCR 43
cDNA source data(35)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(44) Genomic(5) cDNA(35) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000032814 (Evidence)
Ensembl Gene ModelENSMUSG00000068457 (Evidence)
Entrez Gene22290 (Evidence)
UniGene20477
DFCITC1583039, TC1593802, TC1715621
DoTSDT.101340593, DT.101375407, DT.110950138, DT.55180876, DT.87035494, DT.97360318
NIA Mouse Gene IndexU081436
EC1.14.11.-
Consensus CDS ProjectCCDS41216.1
International Mouse Knockout Project StatusUty
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032814 VEGA Gene Model | MGI Sequence Detail 148899 C57BL/6J ±  kb
transcript OTTMUST00000081742 VEGA | MGI Sequence Detail 5208 Not Applicable 
polypeptide OTTMUSP00000043769 VEGA | MGI Sequence Detail 1212 Not Applicable 

For the selected sequences
All sequences(102) RefSeq(25) UniProt(13)
Polymorphisms SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003347 JmjC domain
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR019734 Tetratricopeptide repeat
InterPro IPR013026 Tetratricopeptide repeat-containing domain
InterPro IPR001440 Tetratricopeptide TPR-1
InterPro IPR013105 Tetratricopeptide TPR2
Protein Ontology PR:000017213 histone demethylase UTY
References (Earliest) J:21470 King TR, et al., Deletion mapping by immunoselection against the H-Y histocompatibility antigen further resolves the Sxra region of the mouse Y chromosome and reveals complexity of the Hya locus. Genomics. 1994 Nov 1;24(1):159-68
(Latest) J:201868 Shpargel KB, et al., UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012 Sep;8(9):e1002964
All references(38)
Other
accession IDs
MGD-MRK-11034, MGI:96299

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory