Ldb2
Gene Detail

Symbol Name ID

Ldb2 LIM domain binding 2 MGI:894670

Synonyms

CLIM1, CLIM-1a, CLIM-1b, CLP-36, Ldb3

Feature Type

protein coding gene

Genetic Map

Chromosome 5

24.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr5:44472133-44799707 bp, - strand From NCBI annotation of GRCm38   327575 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Ldb2 ± 2 cM)

Protein SuperFamily: LIM-domain-binding protein
Gene Tree: Ldb2

Human ortholog

LDB2 LIM domain binding 2 NCBI Gene ID 9079
Human Synonyms: CLIM1, LDB1
Human Chr4:16503164-16900424 bp, - strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Homozygous mutation of this gene results in no obvious phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	epithelial structure maintenance, hair follicle development, ...
Component	nucleus, transcription factor complex
Function	enzyme binding, LIM domain binding, ...

External Resources: FuncBase

Expression

Literature Summary: (26 records)
Data Summary: Results (90)    Tissues (83)    Images (8)
Theiler Stages: 2, 3, 4, 5, 15, 17, 18, 19, 20, 21, 23, 26, 28

Assay Type	Results
RNA in situ	75
RT-PCR	15

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(15) cDNA(13) Primer pair(1) Other(1)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000039706 (Evidence)
Entrez Gene	16826 (Evidence)
DFCI	TC1582170, TC1612074, TC1774420
DoTS	DT.101381925, DT.40181101, DT.99822105, DT.99855203
NIA Mouse Gene Index	U026165
Consensus CDS Project	CCDS19271.1
International Mouse Knockout Project Status	Ldb2

Sequences

Length	Strain/Species
genomic	16826	NCBI Gene Model | MGI Sequence Detail	327575	C57BL/6J
transcript	NM_001077398	RefSeq | MGI Sequence Detail	2622	C57BL/6
polypeptide	O55203	UniProt | EBI | MGI Sequence Detail	373	Not Applicable

All sequences(28) RefSeq(4) UniProt(1)

Polymorphisms

SNPs(1567 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002691	LIM-domain binding protein
Protein Ontology	PR:000009737	LIM domain-binding protein 2

Graphical View of Protein Domain Structure

References

(Earliest) J:41552 Agulnick AD, et al., Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins. Nature. 1996 21;384(6606):270-2
(Latest) J:192580 Diaz-Alonso J, et al., The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci. 2012 Nov 21;32(47):16651-65
All references(53)

Other accession IDs

MGI:2140800, MGI:2141166, MGI:894768