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Ldb2 Gene Detail
Summary
  • Symbol
    Ldb2
  • Name
    LIM domain binding 2
  • Synonyms
    CLIM1, CLIM-1a, CLIM-1b, CLP-36, Ldb3
  • Feature Type
    protein coding gene
  • IDs
    MGI:894670
    NCBI Gene: 16826
  • Gene Overview
    MyGene.info: LDB2
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:44472132-44799680 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 24.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2053 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_894670
protein coding gene Chr5:44436079-44799760 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029530
protein coding gene Chr5:43123828-43478950 (-)
A/J MGP_AJ_G0029498
protein coding gene Chr5:41641456-41978763 (-)
AKR/J MGP_AKRJ_G0029446
protein coding gene Chr5:43108441-43445459 (-)
BALB/cJ MGP_BALBcJ_G0029507
protein coding gene Chr5:42119808-42455365 (-)
C3H/HeJ MGP_C3HHeJ_G0029230
protein coding gene Chr5:43097690-43448281 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029961
protein coding gene Chr5:45198709-45549062 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027200
protein coding gene Chr5:38843324-39181117 (-)
CAST/EiJ MGP_CASTEiJ_G0028638
protein coding gene Chr5:42222844-42583485 (-)
CBA/J MGP_CBAJ_G0029199
protein coding gene Chr5:46394126-46772379 (-)
DBA/2J MGP_DBA2J_G0029345
protein coding gene Chr5:41727286-42064559 (-)
FVB/NJ MGP_FVBNJ_G0029305
protein coding gene Chr5:41155181-41489619 (-)
LP/J MGP_LPJ_G0029430
protein coding gene Chr5:43592973-43951447 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029333
protein coding gene Chr5:47182057-47548672 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029994
protein coding gene Chr5:42604260-42957293 (-)
PWK/PhJ MGP_PWKPhJ_G0028362
protein coding gene Chr5:40860047-41194581 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028196
protein coding gene Chr5:42058219-42417569 (-)
WSB/EiJ MGP_WSBEiJ_G0028719
protein coding gene Chr5:42690600-43042535 (-)



Homology
more
  • Human Ortholog
    LDB2, LIM domain binding 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LDB2, LIM domain binding 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CLIM1, LDB1, LDB-2
  • Links
    NCBI Gene ID: 9079
    neXtProt AC: NX_O43679
    UniProt: O43679

  • Chr Location
    4p15.32; chr4:16501534-16898809 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    24 phenotype references
Homozygous mutation of this gene results in no obvious phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039706 Ensembl Gene Model | MGI Sequence Detail 327549 C57BL/6J ±  kb
transcript ENSMUST00000070748 Ensembl | MGI Sequence Detail 2418 Not Applicable  
polypeptide ENSMUSP00000067737 Ensembl | MGI Sequence Detail 373 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 1
    cDNA 13
    Primer pair 1
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2140800, MGI:2141166, MGI:894768
References
more
  • Summaries
    All 85
    Developmental Gene Expression 36
    Diseases 1
    Gene Ontology 10
    Phenotypes 24
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory