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Npm3
Gene Detail
Symbol

Name
ID
Npm3
nucleoplasmin 3
MGI:894653
Synonyms
Nub1
Feature Type
protein coding gene
Genetic Map
Chromosome 19
38.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:45747734-45749591 bp, - strand
From VEGA annotation of GRCm38

  1858 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5083  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Npm3

Human
homologs
Human Homolog NPM3, nucleophosmin/nucleoplasmin 3
NCBI Gene ID 10360
neXtProt AC  NX_O75607
Human Synonyms  PORMIN, TMEM123
Human Chr (Location)  10q24.31; chr10:101781325-101783413 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(6) Targeted(4)
Genomic Mutations involving Npm3 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Npm3 interacts with 47 markers (Mir17, Mir20b, Mir92-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process rRNA processing, rRNA transcription
Component nucleolus, nucleus
Function nucleic acid binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (8)    Tissues (8)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 8
cDNA source data(34)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(36) Genomic(2) cDNA(34)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022715 (Evidence)
Ensembl Gene ModelENSMUSG00000056209 (Evidence)
Entrez Gene18150 (Evidence)
UniGene1406
NIA Mouse Gene IndexU213673, U007097
Consensus CDS ProjectCCDS29865.1
International Mouse Knockout Project StatusNpm3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022715 VEGA Gene Model | MGI Sequence Detail 1858 C57BL/6J ±  kb
transcript OTTMUST00000054481 VEGA | MGI Sequence Detail 888 Not Applicable 
polypeptide OTTMUSP00000026010 VEGA | MGI Sequence Detail 175 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(16 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004301 Nucleoplasmin
InterPro IPR024057 Nucleoplasmin core domain
Protein Ontology PR:000011372 nucleoplasmin-3
References
(Earliest) J:23751 MacArthur CA, et al., Fgf-8, activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis. J Virol. 1995 Apr;69(4):2501-7
(Latest) J:197707 Okuwaki M, et al., Function of homo- and hetero-oligomers of human nucleoplasmin/nucleophosmin family proteins NPM1, NPM2 and NPM3 during sperm chromatin remodeling. Nucleic Acids Res. 2012 Jun;40(11):4861-78
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory