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Rab6a Gene Detail
Summary
  • Symbol
    Rab6a
  • Name
    RAB6A, member RAS oncogene family
  • Synonyms
    2610028L11Rik, Rab6
  • Feature Type
    protein coding gene
  • IDs
    MGI:894313
    NCBI Gene: 19346
  • Gene Overview
    MyGene.info: RAB6A
Location & Maps
more
  • Sequence Map
    Chr7:100607410-100641268 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33859 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.36 cM, cytoband C4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RAB6A, RAB6A, member RAS oncogene family
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RAB6A, RAB6A, member RAS oncogene family
    Orthology source: HomoloGene
  • Synonyms
    RAB6
  • Links
    NCBI Gene ID: 5870
    neXtProt AC: NX_P20340

  • Chr Location
    11q13.3; chr11:73675638-73761156 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    1
  • Gene trapped
    13
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Rab6a
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016494 VEGA Gene Model | MGI Sequence Detail 33859 C57BL/6J ±  kb
transcript OTTMUST00000039813 VEGA | MGI Sequence Detail 3214 Not Applicable  
polypeptide OTTMUSP00000017760 VEGA | MGI Sequence Detail 208 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    194 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013636 ras-related protein Rab-6A
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
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  • All nucleic 231
    cDNA 231

    Microarray probesets 7
Other
Accession IDs
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MGI:1925564, MGI:2141829
References
more
  • Summaries
    All 45
    Developmental Gene Expression 4
    Gene Ontology 12
    Phenotypes 16
  • Earliest
    J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
  • Latest
    J:230729 Shafaq-Zadah M, et al., Persistent cell migration and adhesion rely on retrograde transport of beta(1) integrin. Nat Cell Biol. 2016 Jan;18(1):54-64

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory