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Rab6a
Gene Detail
Symbol

Name
ID
Rab6a
RAB6A, member RAS oncogene family
MGI:894313
Synonyms
2610028L11Rik, Rab6
Feature Type
protein coding gene
Genetic Map
Chromosome 7
54.36 cM, cytoband C4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:100607410-100641268 bp, + strand
From VEGA annotation of GRCm38

  33859 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55697  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAB6A
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab6a

Human
homologs
RAB6A, RAB6A, member RAS oncogene family
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5870
neXtProt AC: NX_P20340

Human Synonyms: RAB6

Human Chr (Location): 11q13.3; chr11:73675638-73761156 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(13) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Rab6a interacts with 321 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (41 annotations)
Process antigen processing and presentation, early endosome to Golgi transport, ...
Component cell, cytoplasmic vesicle, ...
Function ATPase activator activity, ATPase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (133)    Tissues (36)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 114
Western blot 19
cDNA source data(230)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab6a    NEW 
Molecular
reagents
All nucleic(231) cDNA(231)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000016494 (Evidence)
Ensembl Gene Model ENSMUSG00000030704 (Evidence)
Entrez Gene 19346 (Evidence)
UniGene 28650
DFCI TC1573254, TC1587308
DoTS DT.101393084, DT.110984208, DT.536434
NIA Mouse Gene Index U008458, U075357, U364179
Consensus CDS Project CCDS21503.1, CCDS52323.1
International Mouse Phenotyping Consortium Status Rab6a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016494 VEGA Gene Model | MGI Sequence Detail 33859 C57BL/6J ±  kb
transcript OTTMUST00000039813 VEGA | MGI Sequence Detail 3214 Not Applicable 
polypeptide OTTMUSP00000017760 VEGA | MGI Sequence Detail 208 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(199 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013636 ras-related protein Rab-6A
References
(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(47)
Other
accession IDs
MGI:1925564, MGI:2141829

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory