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Rab6a
Gene Detail
 Symbol
Name
ID
Rab6a
RAB6A, member RAS oncogene family
MGI:894313
Synonyms 2610028L11Rik, Rab6
Feature Type protein coding gene
Genetic Map
Chromosome 7
54.36 cM, cytoband C4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:100607410-100641268 bp, + strand
From VEGA annotation of GRCm38

  33859 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55697  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab6a

Human
homologs
Human Homolog RAB6A, RAB6A, member RAS oncogene family
NCBI Gene ID 5870
neXtProt AC  NX_P20340
Human Synonyms  RAB6
Human Chr (Location)  11q13.3; chr11:73675638-73761156 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(13) Targeted(2)
Incidental mutations (data from APF )
Interactions
Rab6a interacts with 321 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process antigen processing and presentation, early endosome to Golgi transport, ...
Component cell, cytoplasmic vesicle, ...
Function ATPase activator activity, ATPase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (133)    Tissues (36)    Images (26)
Theiler Stages: 17, 21, 22, 23, 24, 25, 26, 27, 28
Assay TypeResults
RNA in situ 114
Western blot 19
cDNA source data(230)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(231) cDNA(231)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000016494 (Evidence)
Ensembl Gene ModelENSMUSG00000030704 (Evidence)
Entrez Gene19346 (Evidence)
UniGene28650
DFCITC1573254, TC1587308
DoTSDT.101393084, DT.110984208, DT.536434
NIA Mouse Gene IndexU008458, U075357, U364179
Consensus CDS ProjectCCDS21503.1, CCDS52323.1
International Mouse Knockout Project StatusRab6a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016494 VEGA Gene Model | MGI Sequence Detail 33859 C57BL/6J ±  kb
transcript OTTMUST00000039814 VEGA | MGI Sequence Detail 3110 Not Applicable 
polypeptide OTTMUSP00000017761 VEGA | MGI Sequence Detail 208 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(4) UniProt(4)
Polymorphisms SNPs within 2kb(199 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013636 ras-related protein Rab-6A
References (Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(47)
Other
accession IDs
MGI:1925564, MGI:2141829

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory