Sept8
Gene Detail

Symbol Name ID

Sept8 septin 8 MGI:894310

Synonyms

mKIAA0202, Sepl

Feature Type

protein coding gene

Genetic Map

Chromosome 11

31.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr11:53519257-53549565 bp, + strand From VEGA annotation of GRCm38   30309 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:57205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: septin
Gene Tree: Sept8

Human homologs

Human Homolog		SEPT8, septin 8
NCBI Gene ID		23176
neXtProt AC		NX_Q92599
Human Synonyms		SEP2
Human Chr (Location)		5q31; chr5:132086509-132113561 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	cell cycle
Component	cytoplasm, cytoskeleton, ...
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (38)    Tissues (4)    Images (24)
Theiler Stages: 23

Assay Type	Results
RNA in situ	38

cDNA source data(120)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(126) Genomic(5) cDNA(120) Other(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000005635 (Evidence)
Ensembl Gene Model	ENSMUSG00000018398 (Evidence)
Entrez Gene	20362 (Evidence)
UniGene	274399
DFCI	TC1597892, TC1598826
DoTS	DT.101250317, DT.110537200, DT.532725
NIA Mouse Gene Index	U012599
Consensus CDS Project	CCDS48794.1, CCDS56768.1
International Mouse Knockout Project Status	Sept8

Sequences

Length	Strain/Species
genomic	OTTMUSG00000005635	VEGA Gene Model | MGI Sequence Detail	30309	C57BL/6J
transcript	OTTMUST00000071547	VEGA | MGI Sequence Detail	2801	Not Applicable
polypeptide	OTTMUSP00000036684	VEGA | MGI Sequence Detail	484	Not Applicable

All sequences(61) RefSeq(6) UniProt(5)

Polymorphisms

SNPs(56 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000038	Cell division protein GTP binding
InterPro	IPR016491	Septin
Protein Ontology	PR:000014660	septin-8

References

(Earliest) J:40314 Frazer KA, et al., Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. Genome Res. 1997 May;7(5):495-512
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(34)

Other accession IDs

MGI:2144480