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Sept8
Gene Detail
Symbol

Name
ID
Sept8
septin 8
MGI:894310
Synonyms
mKIAA0202, Sepl
Feature Type
protein coding gene
Genetic Map
Chromosome 11
31.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:53519257-53549565 bp, + strand
From VEGA annotation of GRCm38

  30309 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SEPT8
Protein SuperFamily: septin
Gene Tree: Sept8

Human
homologs
SEPT8, septin 8
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23176
neXtProt AC: NX_Q92599

Human Synonyms: SEP2

Human Chr (Location): 5q31; chr5:132750817-132778284 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Sept8 interacts with 383 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process biological_process
Component cytoplasm, cytoskeleton, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (38)    Tissues (4)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 38
cDNA source data(119)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sept8 ; ZFIN sept8a    NEW 
Molecular
reagents
All nucleic(125) Genomic(5) cDNA(119) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000005635 (Evidence)
Ensembl Gene Model ENSMUSG00000018398 (Evidence)
Entrez Gene 20362 (Evidence)
UniGene 274399
DFCI TC1597892, TC1598826
DoTS DT.101250317, DT.110537200, DT.532725
NIA Mouse Gene Index U012599
Consensus CDS Project CCDS48794.1, CCDS56768.1
International Mouse Phenotyping Consortium Status Sept8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005635 VEGA Gene Model | MGI Sequence Detail 30309 C57BL/6J ±  kb
transcript OTTMUST00000071547 VEGA | MGI Sequence Detail 2801 Not Applicable 
polypeptide OTTMUSP00000036684 VEGA | MGI Sequence Detail 484 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(16) UniProt(5)
Polymorphisms
SNPs within 2kb(199 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016491 Septin
InterPro IPR030646 Septin 8
InterPro IPR030379 Septin-type guanine nucleotide-binding (G) domain
Protein Ontology PR:000014660 septin-8
References
(Earliest) J:40314 Frazer KA, et al., Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. Genome Res. 1997 May;7(5):495-512
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(34)
Other
accession IDs
MGI:2144480

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory