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Sept8
Gene Detail
 Symbol
Name
ID
Sept8
septin 8
MGI:894310
Synonyms mKIAA0202, Sepl
Feature Type protein coding gene
Genetic Map
Chromosome 11
31.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:53519257-53549565 bp, + strand
From VEGA annotation of GRCm38

  30309 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: septin
Gene Tree: Sept8

Human
homologs
Human Homolog SEPT8, septin 8
NCBI Gene ID 23176
neXtProt AC  NX_Q92599
Human Synonyms  SEP2
Human Chr (Location)  5q31; chr5:132750817-132778012 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sept8 interacts with 384 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process cell cycle
Component cytoplasm, cytoskeleton, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (38)    Tissues (4)    Images (24)
Theiler Stages: 23
Assay TypeResults
RNA in situ 38
cDNA source data(119)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(125) Genomic(5) cDNA(119) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000005635 (Evidence)
Ensembl Gene ModelENSMUSG00000018398 (Evidence)
Entrez Gene20362 (Evidence)
UniGene274399
DFCITC1597892, TC1598826
DoTSDT.101250317, DT.110537200, DT.532725
NIA Mouse Gene IndexU012599
Consensus CDS ProjectCCDS48794.1, CCDS56768.1
International Mouse Knockout Project StatusSept8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005635 VEGA Gene Model | MGI Sequence Detail 30309 C57BL/6J ±  kb
transcript OTTMUST00000071547 VEGA | MGI Sequence Detail 2801 Not Applicable 
polypeptide OTTMUSP00000036684 VEGA | MGI Sequence Detail 484 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(12) UniProt(5)
Polymorphisms SNPs within 2kb(199 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000038 Cell division protein GTP binding
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016491 Septin
Protein Ontology PR:000014660 septin-8
References (Earliest) J:40314 Frazer KA, et al., Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. Genome Res. 1997 May;7(5):495-512
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(33)
Other
accession IDs
MGI:2144480

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory