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Rab21 Gene Detail
Summary
  • Symbol
    Rab21
  • Name
    RAB21, member RAS oncogene family
  • Feature Type
    protein coding gene
  • IDs
    MGI:894308
    NCBI Gene: 216344
  • Gene Overview
    MyGene.info: RAB21
Location & Maps
more
  • Sequence Map
    Chr10:115289863-115315591 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25729 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 63.51 cM, cytoband D1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RAB21, RAB21, member RAS oncogene family
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAB21, RAB21, member RAS oncogene family
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23011
    neXtProt AC: NX_Q9UL25

  • Chr Location
    12q21.1; chr12:71754850-71787370 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    3
  • Genomic Mutations
    1 involving Rab21
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020132 Ensembl Gene Model | MGI Sequence Detail 25729 C57BL/6J ±  kb
transcript ENSMUST00000020343 Ensembl | MGI Sequence Detail 1823 Not Applicable  
polypeptide ENSMUSP00000020343 Ensembl | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    267 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 13
  • Earliest
    J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
  • Latest
    J:197013 Ohbayashi N, et al., The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes. Mol Biol Cell. 2012 Feb;23(4):669-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory