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Rab21
Gene Detail
Symbol

Name
ID
Rab21
RAB21, member RAS oncogene family
MGI:894308
Feature Type
protein coding gene
Genetic Map
Chromosome 10
63.51 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:115289863-115315591 bp, - strand
From Ensembl annotation of GRCm38

  25729 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8991  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAB21
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab21

Human
homologs
RAB21, RAB21, member RAS oncogene family
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 23011
neXtProt AC: NX_Q9UL25

Human Chr (Location): 12q21.1; chr12:71754850-71787370 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab21 interacts with 241 markers (Mir7-1, Mir15a, Mir16-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (50)    Tissues (10)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 50
cDNA source data(77)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab21    NEW 
Molecular
reagents
All nucleic(77) cDNA(77)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000020132 (Evidence)
Entrez Gene 216344 (Evidence)
UniGene 21936
DFCI TC1613430, TC1605510, TC1578353
DoTS DT.87048950, DT.101735314
NIA Mouse Gene Index U032234
Consensus CDS Project CCDS24177.1
International Mouse Phenotyping Consortium Status Rab21
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020132 Ensembl Gene Model | MGI Sequence Detail 25729 C57BL/6J ±  kb
transcript ENSMUST00000020343 Ensembl | MGI Sequence Detail 1823 Not Applicable 
polypeptide ENSMUSP00000020343 Ensembl | MGI Sequence Detail 222 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(260 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013594 ras-related protein Rab-21
References
(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:197013 Ohbayashi N, et al., The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes. Mol Biol Cell. 2012 Feb;23(4):669-78
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory