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Gngt2
Gene Detail
 Symbol
Name
ID
Gngt2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
MGI:893584
Feature Type protein coding gene
Genetic Map
Chromosome 11
59.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:95837216-95845734 bp, + strand
From VEGA annotation of GRCm38

  8519 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11325  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 2 western clawed frog; 1 zebrafish

Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gngt2

Human
homologs
Human Homolog GNGT2, guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
NCBI Gene ID 2793
neXtProt AC  NX_O14610
Human Synonyms  G-GAMMA-8, G-GAMMA-C, GNG8, GNG9, GNGT8
Human Chr (Location)  17q21; chr17:49206234-49210574 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(4) Targeted(4)
Genomic Mutations involving Gngt2 (1)
Interactions
Gngt2 interacts with 24 markers (Mir133a-1, Mir133a-2, Mir133b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process G-protein coupled receptor signaling pathway, GTP catabolic process, ...
Component heterotrimeric G-protein complex, membrane, ...
Function signal transducer activity
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (9)    Tissues (2)    Images (9)
Theiler Stages: 23, 28
Assay TypeResults
RNA in situ 9
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(30) Genomic(6) cDNA(23) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001754 (Evidence)
Ensembl Gene ModelENSMUSG00000038811 (Evidence)
Entrez Gene14710 (Evidence)
UniGene46299
NIA Mouse Gene IndexU013234
Consensus CDS ProjectCCDS25284.1
International Mouse Knockout Project StatusGngt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001754 VEGA Gene Model | MGI Sequence Detail 8519 C57BL/6J ±  kb
transcript OTTMUST00000003496 VEGA | MGI Sequence Detail 498 Not Applicable 
polypeptide OTTMUSP00000001688 VEGA | MGI Sequence Detail 69 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(12) UniProt(3)
Polymorphisms All PCR and RFLP(3) : PCR(1) RFLP(2) SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015898 G-protein gamma-like domain
InterPro IPR001770 G-protein, gamma subunit
Protein Ontology PR:000008114 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
References (Earliest) J:34526 Williams CJ, et al., G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2144460

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory