Gpr19
Gene Detail

Symbol Name ID

Gpr19 G protein-coupled receptor 19 MGI:892973

Feature Type

protein coding gene

Genetic Map

Chromosome 6

65.77 cM, cytoband G1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr6:134869108-134897925 bp, - strand From VEGA annotation of GRCm38   28818 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Gpr19 ± 2 cM)

Protein SuperFamily: probable G protein-coupled receptor 19
Gene Tree: Gpr19

Human ortholog

GPR19 G protein-coupled receptor 19 NCBI Gene ID 2842
Human Chr12:12813995-12849121 bp, - strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(60) : Targeted(3) Gene trapped(57)
 

Homozygous mutation of this gene results in increased anxiety-like behavior.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	G-protein coupled receptor signaling pathway, signal transduction
Component	integral to membrane, membrane, ...
Function	G-protein coupled receptor activity, signal transducer activity

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (357)    Tissues (121)    Images (74)
Theiler Stages: 2, 3, 23, 28

Assay Type	Results
RNA in situ	148
In situ reporter (knock in)	89
RT-PCR	120

cDNA source data(18)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(21) cDNA(18) Primer pair(3)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000024355 (Evidence)
Ensembl Gene Model	ENSMUSG00000032641 (Evidence)
Entrez Gene	14760 (Evidence)
UniGene	4787
DFCI	TC1583398, TC1632077, TC1635617, TC1639727, TC1672891, TC1773976
DoTS	DT.101257016, DT.101325547, DT.101374062, DT.101374063, DT.40168864, DT.91578631, DT.97391599, DT.99832479
NIA Mouse Gene Index	U027958
Consensus CDS Project	CCDS20641.1, CCDS51937.1
International Mouse Knockout Project Status	Gpr19

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024355	VEGA Gene Model | MGI Sequence Detail	28818	C57BL/6J
transcript	OTTMUST00000059660	VEGA | MGI Sequence Detail	1610	Not Applicable
polypeptide	OTTMUSP00000029039	VEGA | MGI Sequence Detail	415	Not Applicable

All sequences(75) RefSeq(17) UniProt(1)

Polymorphisms

SNPs(139 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000276	GPCR, rhodopsin-like
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM
Protein Ontology	PR:000001520	G-protein coupled receptor 19

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(38)