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Gpr19 Gene Detail
Summary
  • Symbol
    Gpr19
  • Name
    G protein-coupled receptor 19
  • Feature Type
    protein coding gene
  • IDs
    MGI:892973
    NCBI Gene: 14760
  • Gene Overview
    MyGene.info: GPR19
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:134869093-134898578 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 65.77 cM, cytoband G1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    330 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_892973
protein coding gene Chr6:134869092-134899482 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031409
protein coding gene Chr6:139164420-139195481 (-)
A/J MGP_AJ_G0031385
protein coding gene Chr6:133704410-133734076 (-)
AKR/J MGP_AKRJ_G0031312
protein coding gene Chr6:137759170-137791143 (-)
BALB/cJ MGP_BALBcJ_G0031391
protein coding gene Chr6:133518352-133548623 (-)
C3H/HeJ MGP_C3HHeJ_G0031113
protein coding gene Chr6:137803060-137832989 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031851
protein coding gene Chr6:142943004-142972473 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028983
protein coding gene Chr6:132848414-132877484 (-)
CAST/EiJ MGP_CASTEiJ_G0030482
protein coding gene Chr6:137218234-137247636 (-)
CBA/J MGP_CBAJ_G0031072
protein coding gene Chr6:148275313-148305141 (-)
DBA/2J MGP_DBA2J_G0031230
protein coding gene Chr6:132553785-132583293 (-)
FVB/NJ MGP_FVBNJ_G0031180
protein coding gene Chr6:131469095-131499052 (-)
LP/J MGP_LPJ_G0031314
protein coding gene Chr6:139271057-139302799 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031220
protein coding gene Chr6:152305339-152336608 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031884
protein coding gene Chr6:137497886-137527205 (-)
PWK/PhJ MGP_PWKPhJ_G0030207
protein coding gene Chr6:131044734-131074672 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030031
protein coding gene Chr6:135667793-135697398 (-)
WSB/EiJ MGP_WSBEiJ_G0030573
protein coding gene Chr6:138130346-138161254 (-)



Homology
more
  • Human Ortholog
    GPR19, G protein-coupled receptor 19
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GPR19, G protein-coupled receptor 19
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 2842
    neXtProt AC: NX_Q15760
    UniProt: Q15760

  • Chr Location
    12p13.1; chr12:12659691-12716305 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in increased anxiety-like behavior.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032641 Ensembl Gene Model | MGI Sequence Detail 29486 C57BL/6J ±  kb
transcript ENSMUST00000066107 Ensembl | MGI Sequence Detail 1647 Not Applicable  
polypeptide ENSMUSP00000066287 Ensembl | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 19
    Primer pair 3

    Microarray probesets 4
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:246963 Badgandi HB, et al., Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins. J Cell Biol. 2017 Mar 06;216(3):743-760

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory