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Klk1b11
Gene Detail
Symbol

Name
ID
Klk1b11
kallikrein 1-related peptidase b11
MGI:892023
Synonyms
Klk11, mGK-11
Feature Type
protein coding gene
Genetic Map
Chromosome 7
28.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:43995877-43999875 bp, + strand
From VEGA annotation of GRCm38

  3999 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

HCOP human homology predictions: KLK3
Protein SuperFamily: trypsin
Gene Tree: Klk1b11

Human
homologs
KLK3, kallikrein-related peptidase 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 354
neXtProt AC: NX_P07288

Human Synonyms: APS, hK3, KLK2A1, PSA

Human Chr (Location): 19q13.41; chr19:50854915-50877702 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klk1b11 interacts with 14 markers (Mir27a, Mir27b, Mir92-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component extracellular exosome, nucleus
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(35)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(118) Genomic(83) cDNA(35)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027240 (Evidence)
Ensembl Gene Model ENSMUSG00000044485 (Evidence)
Entrez Gene 16613 (Evidence)
UniGene 443378
NIA Mouse Gene Index U182668
EC 3.4.21.35
Consensus CDS Project CCDS21192.1
International Mouse Phenotyping Consortium Status Klk1b11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027240 VEGA Gene Model | MGI Sequence Detail 3999 C57BL/6J ±  kb
transcript OTTMUST00000067360 VEGA | MGI Sequence Detail 863 Not Applicable 
polypeptide OTTMUSP00000033879 VEGA | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(225 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009604 kallikrein 1-related peptidase b11
References
(Earliest) J:8756 Evans BA, et al., Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus. J Biol Chem. 1987 Jun 15;262(17):8027-34
(Latest) J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory