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Klk1b11 Gene Detail
Summary
  • Symbol
    Klk1b11
  • Name
    kallikrein 1-related peptidase b11
  • Synonyms
    Klk11, mGK-11
  • Feature Type
    protein coding gene
  • IDs
    MGI:892023
    NCBI Gene: 16613
Location & Maps
more
  • Sequence Map
    Chr7:43995877-43999875 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3999 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.48 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    KLK1, kallikrein 1
  • Vertebrate Orthologs
    16
  • Human Ortholog
    KLK1, kallikrein 1
    Orthology source: HGNC
  • Synonyms
    hK1, Klk6, KLKR
  • Links
    NCBI Gene ID: 3816
    neXtProt AC: NX_P06870

  • Chr Location
    19q13.3; chr19:50819146-50823787 (-)  GRCh38.p2

  • Human Ortholog
    KLK3, kallikrein related peptidase 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APS, hK3, KLK2A1, PSA
  • Links
    NCBI Gene ID: 354
    neXtProt AC: NX_P07288

  • Chr Location
    19q13.41; chr19:50854915-50877702 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human KLK1 associations

Human Disease Mouse Models
       Kallikrein, Decreased Urinary Activity of   OMIM: 615953
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Other Mouse Links
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027240 VEGA Gene Model | MGI Sequence Detail 3999 C57BL/6J ±  kb
transcript OTTMUST00000067360 VEGA | MGI Sequence Detail 863 Not Applicable  
polypeptide OTTMUSP00000033879 VEGA | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    212 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009604 kallikrein 1-related peptidase b11
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 118
    Genomic 83
    cDNA 35

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Gene Ontology 3
  • Earliest
    J:8756 Evans BA, et al., Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus. J Biol Chem. 1987 Jun 15;262(17):8027-34
  • Latest
    J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory