Klk1b21
Gene Detail

Symbol Name ID

Klk1b21 kallikrein 1-related peptidase b21 MGI:892022

Synonyms

Klk21, mGk-21

Feature Type

protein coding gene

Genetic Map

Chromosome 7

28.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:44102292-44106574 bp, + strand From Ensembl annotation of GRCm38   4283 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Klk1b21

Human homologs

Human Homolog		KLK3, kallikrein-related peptidase 3
NCBI Gene ID		354
neXtProt AC		NX_P07288
Human Synonyms		APS, hK3, KLK2A1, PSA
Human Chr (Location)		19q13.41; chr19:51358171-51364020 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	proteolysis
Component	extracellular space
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (76)    Tissues (10)   
Theiler Stages: 1, 2, 4, 11, 15, 18, 28

Assay Type	Results
RT-PCR	76

cDNA source data(10)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(93) Genomic(82) cDNA(10) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000066516 (Evidence)
Entrez Gene	16616 (Evidence)
UniGene	443292
EC	3.4.21.35
Consensus CDS Project	CCDS21195.1
International Mouse Knockout Project Status	Klk1b21

Sequences

Length	Strain/Species
genomic	ENSMUSG00000066516	Ensembl Gene Model | MGI Sequence Detail	4283	C57BL/6J
transcript	ENSMUST00000085455	Ensembl | MGI Sequence Detail	898	Not Applicable
polypeptide	ENSMUSP00000082582	Ensembl | MGI Sequence Detail	261	Not Applicable

All sequences(15) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(117 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000009606	kallikrein 1-related peptidase b21

References

(Earliest) J:8756 Evans BA, et al., Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus. J Biol Chem. 1987 Jun 15;262(17):8027-34
(Latest) J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41
All references(25)