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Klk1b21
Gene Detail
 Symbol
Name
ID
Klk1b21
kallikrein 1-related peptidase b21
MGI:892022
Synonyms Klk21, mGk-21
Feature Type protein coding gene
Genetic Map
Chromosome 7
28.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:44102292-44106574 bp, + strand
From Ensembl annotation of GRCm38

  4283 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Klk1b21

Human
homologs
Human Homolog KLK3, kallikrein-related peptidase 3
NCBI Gene ID 354
neXtProt AC  NX_P07288
Human Synonyms  APS, hK3, KLK2A1, PSA
Human Chr (Location)  19q13.41; chr19:50854915-50860764 (+)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component extracellular space, nucleus
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (76)    Tissues (10)   
Theiler Stages: 1, 2, 4, 11, 15, 18, 28
Assay TypeResults
RT-PCR 76
cDNA source data(10)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(93) Genomic(82) cDNA(10) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000066516 (Evidence)
Entrez Gene16616 (Evidence)
UniGene443292
EC3.4.21.35
Consensus CDS ProjectCCDS21195.1
International Mouse Knockout Project StatusKlk1b21
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066516 Ensembl Gene Model | MGI Sequence Detail 4283 C57BL/6J ±  kb
transcript ENSMUST00000085455 Ensembl | MGI Sequence Detail 898 Not Applicable 
polypeptide ENSMUSP00000082582 Ensembl | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(295 from dbSNP Build 137)    SNPs within 2kb including multiple locations(333)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009606 kallikrein 1-related peptidase b21
References (Earliest) J:8756 Evans BA, et al., Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus. J Biol Chem. 1987 Jun 15;262(17):8027-34
(Latest) J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory