Klk1b5
Gene Detail

Symbol Name ID

Klk1b5 kallikrein 1-related peptidase b5 MGI:892020

Synonyms

Klk5, mGK-5

Feature Type

protein coding gene

Genetic Map

Chromosome 7

28.73 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr7:44216474-44220703 bp, + strand From VEGA annotation of GRCm38   4230 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Klk1b5

Human homologs

Human Homolog		KLK3, kallikrein-related peptidase 3
NCBI Gene ID		354
neXtProt AC		NX_P07288
Human Synonyms		APS, hK3, KLK2A1, PSA
Human Chr (Location)		19q13.41; chr19:51358171-51364020 (+)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	proteolysis
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (40)    Tissues (11)   
Theiler Stages: 1, 2, 4, 11, 15, 18, 26, 28

Assay Type	Results
RT-PCR	40

cDNA source data(5)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(91) Genomic(83) cDNA(5) Primer pair(3)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000027272 (Evidence)
Ensembl Gene Model	ENSMUSG00000066512 (Evidence)
Entrez Gene	16622 (Evidence)
EC	3.4.21.35
Consensus CDS Project	CCDS21201.1
International Mouse Knockout Project Status	Klk1b5

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027272	VEGA Gene Model | MGI Sequence Detail	4230	C57BL/6J
transcript	OTTMUST00000067416	VEGA | MGI Sequence Detail	862	Not Applicable
polypeptide	OTTMUSP00000033921	VEGA | MGI Sequence Detail	261	Not Applicable

All sequences(18) RefSeq(2) UniProt(1)

Polymorphisms

PCR(1) : SNPs(124 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000009613	kallikrein 1-related peptidase b5

References

(Earliest) J:7072 Mason AJ, et al., Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Nature. 1983 May 26;303(5915):300-7
(Latest) J:121918 Schwab KR, et al., Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development. BMC Biol. 2007;5:15
All references(27)