Klk1b8
Gene Detail

Symbol Name ID

Klk1b8 kallikrein 1-related peptidase b8 MGI:892018

Synonyms

Klk8, MGC:18615, mGK-8, TADG14

Feature Type

protein coding gene

Genetic Map

Chromosome 7

28.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:43950664-43954941 bp, + strand From VEGA annotation of GRCm38   4278 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Klk1b8

Human homologs

Human Homolog		KLK3, kallikrein-related peptidase 3
NCBI Gene ID		354
neXtProt AC		NX_P07288
Human Synonyms		APS, hK3, KLK2A1, PSA
Human Chr (Location)		19q13.41; chr19:51358171-51364020 (+)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	proteolysis
Component	cellular_component
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

cDNA source data(19)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(101) Genomic(82) cDNA(19)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000027232 (Evidence)
Ensembl Gene Model	ENSMUSG00000063089 (Evidence)
Entrez Gene	16624 (Evidence)
UniGene	435488
NIA Mouse Gene Index	U294541
EC	3.4.21.35
Consensus CDS Project	CCDS21189.1
International Mouse Knockout Project Status	Klk1b8

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027232	VEGA Gene Model | MGI Sequence Detail	4278	C57BL/6J
transcript	OTTMUST00000067344	VEGA | MGI Sequence Detail	859	Not Applicable
polypeptide	OTTMUSP00000033868	VEGA | MGI Sequence Detail	261	Not Applicable

All sequences(16) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(94 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000009614	kallikrein 1-related peptidase b8

References

(Earliest) J:8334 Fahnestock M, et al., The sequence of a cDNA clone coding for a novel kallikrein from mouse submaxillary gland. Nucleic Acids Res. 1986 Jun 25;14(12):4823-35
(Latest) J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41
All references(25)