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Klk1b8 Gene Detail
Summary
  • Symbol
    Klk1b8
  • Name
    kallikrein 1-related peptidase b8
  • Synonyms
    Klk8, MGC:18615, mGK-8, TADG14
  • Feature Type
    protein coding gene
  • IDs
    MGI:892018
    NCBI Gene: 16624
Location & Maps
more
  • Sequence Map
    Chr7:43950664-43954941 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4278 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.43 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    KLK3, kallikrein related peptidase 3
  • Vertebrate Orthologs
    16
  • Human Ortholog
    KLK3, kallikrein related peptidase 3
    Orthology source: HomoloGene
  • Synonyms
    APS, hK3, KLK2A1, PSA
  • Links
    NCBI Gene ID: 354
    neXtProt AC: NX_P07288

  • Chr Location
    19q13.41; chr19:50854915-50877702 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027232 VEGA Gene Model | MGI Sequence Detail 4278 C57BL/6J ±  kb
transcript OTTMUST00000067344 VEGA | MGI Sequence Detail 859 Not Applicable  
polypeptide OTTMUSP00000033868 VEGA | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    188 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000009614 kallikrein 1-related peptidase b8
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
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  • All nucleic 101
    Genomic 82
    cDNA 19

    Microarray probesets 4
References
more
  • Summaries
    All 24
    Gene Ontology 3
  • Earliest
    J:8334 Fahnestock M, et al., The sequence of a cDNA clone coding for a novel kallikrein from mouse submaxillary gland. Nucleic Acids Res. 1986 Jun 25;14(12):4823-35
  • Latest
    J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory