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H2-Bl
Gene Detail
Symbol

Name
ID
H2-Bl
histocompatibility 2, blastocyst
MGI:892004
Synonyms
blastocyst MHC
Feature Type
protein coding gene
Genetic Map
Chromosome 17
18.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:36080115-36084223 bp, - strand
From VEGA annotation of GRCm38

  4109 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128352  Vertebrate Homology Class
1 human; 11 mouse; 12 rat; 1 chimpanzee; 1 rhesus macaque; 24 chicken; 7 zebrafish

Protein SuperFamily: class I histocompatibility antigen
Gene Tree: H2-Bl

Human
homologs
Human Homolog HLA-A, major histocompatibility complex, class I, A
NCBI Gene ID 3105
neXtProt AC  NX_P01892, NX_P04439, NX_P30443, NX_P30450
Human Synonyms  HLAA
Human Chr (Location)  6p21.3; chr6:29942470-29945884 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human HLA-A
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Genomic Mutations involving H2-Bl (1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (87)    Tissues (19)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 75
RT-PCR 12
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) Genomic(2) cDNA(3) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037291 (Evidence)
Ensembl Gene ModelENSMUSG00000073406 (Evidence)
Entrez Gene14963 (Evidence)
DFCITC1688985, TC1593905, TC1586030
NIA Mouse Gene IndexU041301
International Mouse Knockout Project StatusH2-Bl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037291 VEGA Gene Model | MGI Sequence Detail 4109 C57BL/6J ±  kb
transcript OTTMUST00000096216 VEGA | MGI Sequence Detail 862 Not Applicable 
polypeptide OTTMUSP00000053733 VEGA | MGI Sequence Detail 257 Not Applicable 

For the selected sequences
All sequences(106) RefSeq(6) UniProt(24)
Polymorphisms
SNPs within 2kb(182 from dbSNP Build 137)    SNPs within 2kb including multiple locations(194)
Protein-related
information
ResourceIDDescription
InterPro IPR003597 Immunoglobulin C1-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
InterPro IPR011162 MHC classes I/II-like antigen recognition protein
InterPro IPR001039 MHC class I, alpha chain, alpha1/alpha2
InterPro IPR011161 MHC class I-like antigen recognition
References
(Earliest) J:37998 Sipes SL, et al., A new major histocompatibility complex class I b gene expressed in the mouse blastocyst and placenta. Immunogenetics. 1996;45(2):108-20
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(18)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory