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Klk1b16
Gene Detail
 Symbol
Name
ID
Klk1b16
kallikrein 1-related peptidase b16
MGI:891982
Synonyms Klk16, mGk-16
Feature Type protein coding gene
Genetic Map
Chromosome 7
28.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:44136767-44141607 bp, + strand
From VEGA annotation of GRCm38

  4841 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Klk1b16

Human
homologs
Human Homolog KLK3, kallikrein-related peptidase 3
NCBI Gene ID 354
neXtProt AC  NX_P07288
Human Synonyms  APS, hK3, KLK2A1, PSA
Human Chr (Location)  19q13.41; chr19:50854915-50860764 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klk1b16 interacts with 10 markers (Mir23b, Mir325, Mir350, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component nucleus
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(50)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(132) Genomic(82) cDNA(50)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000027255 (Evidence)
Ensembl Gene ModelENSMUSG00000038968 (Evidence)
Entrez Gene16615 (Evidence)
UniGene440887
DFCITC1584516, TC1767717
NIA Mouse Gene IndexU040123
EC3.4.21.54
Consensus CDS ProjectCCDS21197.1
International Mouse Knockout Project StatusKlk1b16
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027255 VEGA Gene Model | MGI Sequence Detail 4841 C57BL/6J ±  kb
transcript OTTMUST00000067394 VEGA | MGI Sequence Detail 1384 Not Applicable 
polypeptide OTTMUSP00000033903 VEGA | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(235 from dbSNP Build 137)    SNPs within 2kb including multiple locations(267)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009605 kallikrein 1-related peptidase b16
References (Earliest) J:8756 Evans BA, et al., Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus. J Biol Chem. 1987 Jun 15;262(17):8027-34
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory