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Klk1b26
Gene Detail
Symbol

Name
ID
Klk1b26
kallikrein 1-related petidase b26
MGI:891981
Synonyms
Egfbp2, EGF-BP type B, Klk26, mGK-26, PRECE-2
Feature Type
protein coding gene
Genetic Map
Chromosome 7
28.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:44012678-44016965 bp, + strand
From Ensembl annotation of GRCm38

  4288 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

HCOP human homology predictions: KLK3
Protein SuperFamily: trypsin
Gene Tree: Klk1b26

Human
homologs
KLK3, kallikrein-related peptidase 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 354
neXtProt AC: NX_P07288

Human Synonyms: APS, hK3, KLK2A1, PSA

Human Chr (Location): 19q13.41; chr19:50854915-50877702 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klk1b26 interacts with 10 markers (Mir23b, Mir218-2, Mir350, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process brain renin-angiotensin system, proteolysis, ...
Component extracellular exosome, extracellular space, ...
Function endopeptidase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000053719 (Evidence)
Entrez Gene 16618 (Evidence)
EC 3.4.21.35
Consensus CDS Project CCDS39938.1
International Mouse Phenotyping Consortium Status Klk1b26
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053719 Ensembl Gene Model | MGI Sequence Detail 4288 C57BL/6J ±  kb
transcript ENSMUST00000048945 Ensembl | MGI Sequence Detail 873 Not Applicable 
polypeptide ENSMUSP00000047488 Ensembl | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(294 from dbSNP Build 137)    SNPs within 2kb including multiple locations(476)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009609 kallikrein 1-related peptidase b26
References
(Earliest) J:32312 Richards RI, et al., Mouse glandular kallikrein genes. Nucleotide sequence of cloned cDNA coding for a member of the kallikrein arginyl esteropeptidase group of serine proteases. J Biol Chem. 1982 Mar 25;257(6):2758-61
(Latest) J:121666 Itoh S, et al., Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium. Circulation. 2006 Apr 11;113(14):1787-98
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory