Klk1b27
Gene Detail

Symbol Name ID

Klk1b27 kallikrein 1-related peptidase b27 MGI:891980

Synonyms

Klk21l, Klk27, mGK-27

Feature Type

protein coding gene

Genetic Map

Chromosome 7

28.54 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:44052290-44056705 bp, + strand From VEGA annotation of GRCm38   4416 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68141  Vertebrate Homology Class
1 human; 14 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Klk1b27

Human homologs

Human Homolog		KLK3, kallikrein-related peptidase 3
NCBI Gene ID		354
neXtProt AC		NX_P07288
Human Synonyms		APS, hK3, KLK2A1, PSA
Human Chr (Location)		19q13.41; chr19:51358171-51364020 (+)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	proteolysis
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (16)    Tissues (2)   
Theiler Stages: 28

Assay Type	Results
RT-PCR	16

cDNA source data(5)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(7) Genomic(1) cDNA(5) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000027241 (Evidence)
Ensembl Gene Model	ENSMUSG00000063177 (Evidence)
Entrez Gene	16619 (Evidence)
UniGene	445911
DFCI	TC1595362
NIA Mouse Gene Index	U008029
EC	3.4.21.-, 3.4.21.4
Consensus CDS Project	CCDS21194.1
International Mouse Knockout Project Status	Klk1b27

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027241	VEGA Gene Model | MGI Sequence Detail	4416	C57BL/6J
transcript	OTTMUST00000067361	VEGA | MGI Sequence Detail	882	Not Applicable
polypeptide	OTTMUSP00000033880	VEGA | MGI Sequence Detail	263	Not Applicable

All sequences(15) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(76 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000009610	kallikrein 1-related peptidase b27

References

(Earliest) J:7072 Mason AJ, et al., Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Nature. 1983 May 26;303(5915):300-7
(Latest) J:111453 Lundwall A, et al., A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem. 2006 Jun;387(6):637-41
All references(24)

Other accession IDs

MGI:1354722