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Vps45 Gene Detail
Summary
  • Symbol
    Vps45
  • Name
    vacuolar protein sorting 45
  • Synonyms
    mVps45
  • Feature Type
    protein coding gene
  • IDs
    MGI:891965
    NCBI Gene: 22365
  • Gene Overview
    MyGene.info: VPS45
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:95999832-96058455 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.65 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    318 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_891965
protein coding gene Chr3:95999832-96058466 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027603
protein coding gene Chr3:96796611-96861823 (-)
A/J MGP_AJ_G0027562
protein coding gene Chr3:93757546-93817798 (-)
AKR/J MGP_AKRJ_G0027529
protein coding gene Chr3:95952807-96019364 (-)
BALB/cJ MGP_BALBcJ_G0027574
protein coding gene Chr3:93542273-93601159 (-)
C3H/HeJ MGP_C3HHeJ_G0027307
protein coding gene Chr3:96247747-96306058 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028022
protein coding gene Chr3:100346208-100413410 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025362
protein coding gene Chr3:90083997-90145247 (-)
CAST/EiJ MGP_CASTEiJ_G0026757
protein coding gene Chr3:95535734-95594805 (-)
CBA/J MGP_CBAJ_G0027284
protein coding gene Chr3:104028512-104095623 (-)
DBA/2J MGP_DBA2J_G0027423
protein coding gene Chr3:93056757-93115876 (-)
FVB/NJ MGP_FVBNJ_G0027394
protein coding gene Chr3:91132010-91190366 (-)
LP/J MGP_LPJ_G0027532
protein coding gene Chr3:98105642-98166165 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027421
protein coding gene Chr3:110137647-110199728 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028076
protein coding gene Chr3:95590712-95652187 (-)
PWK/PhJ MGP_PWKPhJ_G0026485
protein coding gene Chr3:92950870-93009717 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026306
protein coding gene Chr3:93887369-93951637 (-)
WSB/EiJ MGP_WSBEiJ_G0026839
protein coding gene Chr3:95990192-96049423 (-)



Homology
more
  • Human Ortholog
    VPS45, vacuolar protein sorting 45 homolog
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VPS45, vacuolar protein sorting 45 homolog
    Orthology source: HomoloGene, HGNC
  • Synonyms
    H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A
  • Links
    NCBI Gene ID: 11311
    neXtProt AC: NX_Q9NRW7
    UniProt: Q9NRW7

  • Chr Location
    1q21.2; chr1:150067293-150145327 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22365 NCBI Gene Model | MGI Sequence Detail 58624 C57BL/6J ±  kb
transcript NM_013841 RefSeq | MGI Sequence Detail 2643 C57BL/6  
polypeptide P97390 UniProt | EBI | MGI Sequence Detail 570 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139732, MGI:2140005
References
more
  • Summaries
    All 31
    Diseases 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:41065 Pevsner J, et al., Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking. Gene. 1996 Dec 12;183(1-2):7-14
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory