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Cyp4a10
Gene Detail
Symbol

Name
ID
Cyp4a10
cytochrome P450, family 4, subfamily a, polypeptide 10
MGI:88611
Synonyms
Cyp4a, D4Rp1, RP1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
53.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(34)
Sequence Map
Chr4:115518264-115533649 bp, + strand
From VEGA annotation of GRCm38

  15386 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128044  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee

Protein SuperFamily: cytochrome P450 CYP4B1
Gene Tree: Cyp4a10

Human
homologs
Human Homolog CYP4A11, cytochrome P450, family 4, subfamily A, polypeptide 11
NCBI Gene ID 1579
neXtProt AC  NX_Q02928
Human Synonyms  CP4Y, CYP4A2, CYP4AII
Human Chr (Location)  1p33; chr1:46929174-46941484 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display salt-sensitive hypertension, decrease sodium excretion, and decreased urine output.
 
Interactions
Cyp4a10 interacts with 112 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (44)    Tissues (44)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 32
RT-PCR 12
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) Genomic(4) cDNA(13) Primer pair(2) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000008614 (Evidence)
Ensembl Gene ModelENSMUSG00000066072 (Evidence)
Entrez Gene13117 (Evidence)
DFCITC1579925, TC1595997, TC1643154
EC1.14.15.3
Consensus CDS ProjectCCDS18492.1
International Mouse Knockout Project StatusCyp4a10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008614 VEGA Gene Model | MGI Sequence Detail 15386 C57BL/6J ±  kb
transcript OTTMUST00000019512 VEGA | MGI Sequence Detail 2109 Not Applicable 
polypeptide OTTMUSP00000008953 VEGA | MGI Sequence Detail 509 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(7)
Polymorphisms
RFLP(7) : SNPs within 2kb(174 from dbSNP Build 137)    SNPs within 2kb including multiple locations(256)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006246 cytochrome P450 4A10
References
(Earliest) J:13884 Elliott RW, Identification and mapping of new loci using cloned cDNA. Mouse News Lett. 1981;64:87
(Latest) J:171050 Thiagarajan RD, et al., Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
All references(67)
Other
accession IDs
MGD-MRK-14013, MGD-MRK-2333, MGD-MRK-2334, MGD-MRK-6982, MGI:2140347

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory