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Cyp4a10 Gene Detail
Summary
  • Symbol
    Cyp4a10
  • Name
    cytochrome P450, family 4, subfamily a, polypeptide 10
  • Synonyms
    Cyp4a, D4Rp1, Msp-3, RP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:88611
    NCBI Gene: 13117
  • Gene Overview
    MyGene.info: CYP4A11
Location & Maps
more
  • Sequence Map
    Chr4:115518264-115533649 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15386 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.05 cM
  • Mapping Data
    34 experiments
Homology
more
  • Human Ortholog
    CYP4A11, cytochrome P450 family 4 subfamily A member 11
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CYP4A11, cytochrome P450 family 4 subfamily A member 11
    Orthology source: HomoloGene
  • Synonyms
    CP4Y, CYP4A2, CYP4AII
  • Links
    NCBI Gene ID: 1579
    neXtProt AC: NX_Q02928

  • Chr Location
    1p33; chr1:46929174-46941499 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Cyp4a10
  • Incidental Mutations
Mice homozygous for a null mutation display salt-sensitive hypertension, decrease sodium excretion, and decreased urine output.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008614 VEGA Gene Model | MGI Sequence Detail 15386 C57BL/6J ±  kb
transcript OTTMUST00000019512 VEGA | MGI Sequence Detail 2109 Not Applicable  
polypeptide OTTMUSP00000008953 VEGA | MGI Sequence Detail 509 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    124 from dbSNP Build 142
  • RFLP
Protein
Information
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Molecular
Reagents
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  • All nucleic 20
    Genomic 4
    cDNA 13
    Primer pair 2
    Other 1

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-14013, MGD-MRK-2333, MGD-MRK-2334, MGD-MRK-6982, MGI:2140347
References
more
  • Summaries
    All 65
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:13884 Elliott RW, Identification and mapping of new loci using cloned cDNA. Mouse News Lett. 1981;64:87
  • Latest
    J:216177 Labialle S, et al., The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory