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Cyp4a10
Gene Detail
Symbol

Name
ID
Cyp4a10
cytochrome P450, family 4, subfamily a, polypeptide 10
MGI:88611
Synonyms
Cyp4a, D4Rp1, RP1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
53.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(34)
Sequence Map
Chr4:115518264-115533649 bp, + strand
From VEGA annotation of GRCm38

  15386 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128044  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee

HCOP human homology predictions: CYP4A11
Protein SuperFamily: cytochrome P450 CYP4B1
Gene Tree: Cyp4a10

Human
homologs
CYP4A11, cytochrome P450, family 4, subfamily A, polypeptide 11
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1579
neXtProt AC: NX_Q02928

Human Synonyms: CP4Y, CYP4A2, CYP4AII

Human Chr (Location): 1p33; chr1:46929174-46941499 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Genomic Mutations involving Cyp4a10 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation display salt-sensitive hypertension, decrease sodium excretion, and decreased urine output.
 
Interactions
Cyp4a10 interacts with 112 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (44)    Tissues (44)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 32
RT-PCR 12
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) Genomic(4) cDNA(13) Primer pair(2) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000008614 (Evidence)
Ensembl Gene Model ENSMUSG00000066072 (Evidence)
Entrez Gene 13117 (Evidence)
DFCI TC1579925, TC1595997, TC1643154
EC 1.14.15.3
Consensus CDS Project CCDS18492.1
International Mouse Phenotyping Consortium Status Cyp4a10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008614 VEGA Gene Model | MGI Sequence Detail 15386 C57BL/6J ±  kb
transcript OTTMUST00000019512 VEGA | MGI Sequence Detail 2109 Not Applicable 
polypeptide OTTMUSP00000008953 VEGA | MGI Sequence Detail 509 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(7) : SNPs within 2kb(174 from dbSNP Build 137)    SNPs within 2kb including multiple locations(256)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006246 cytochrome P450 4A10
References
(Earliest) J:13884 Elliott RW, Identification and mapping of new loci using cloned cDNA. Mouse News Lett. 1981;64:87
(Latest) J:216177 Labialle S, et al., The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30
All references(67)
Other
accession IDs
MGD-MRK-14013, MGD-MRK-2333, MGD-MRK-2334, MGD-MRK-6982, MGI:2140347

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory