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Cyp2f2
Gene Detail
Symbol

Name
ID
Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
MGI:88608
Synonyms
Cyp2f
Feature Type
protein coding gene
Genetic Map
Chromosome 7
15.82 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:27119909-27133660 bp, + strand
From VEGA annotation of GRCm38

  13752 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:73898  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2f2

Human
homologs
Human Homolog CYP2F1, cytochrome P450, family 2, subfamily F, polypeptide 1
NCBI Gene ID 1572
neXtProt AC  NX_P24903
Human Synonyms  C2F1, CYP2F
Human Chr (Location)  19q13.2; chr19:41114448-41128376 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit resistance to napthalene-induced toxicity in the lungs.
 
Interactions
Cyp2f2 interacts with 46 markers (Mir7-1, Mir7-2, Mir7b, ...)
Expression
Literature Summary: (13 records)
Data Summary: Results (147)    Tissues (115)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 133
RT-PCR 14
cDNA source data(298)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(301) cDNA(299) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027204 (Evidence)
Ensembl Gene ModelENSMUSG00000052974 (Evidence)
Entrez Gene13107 (Evidence)
UniGene4515
DFCITC1572625, TC1627137
DoTSDT.536563, DT.91438009, DT.97370632
NIA Mouse Gene IndexU099319, U217377
EC1.14.14.-
Consensus CDS ProjectCCDS21010.1
International Mouse Knockout Project StatusCyp2f2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027204 VEGA Gene Model | MGI Sequence Detail 13752 C57BL/6J ±  kb
transcript OTTMUST00000067266 VEGA | MGI Sequence Detail 1866 Not Applicable 
polypeptide OTTMUSP00000033816 VEGA | MGI Sequence Detail 491 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(143 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR020469 Cytochrome P450, CYP2 family
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006238 cytochrome P450 2F2
References
(Earliest) J:10678 Nhamburo PT, et al., The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping. Biochemistry. 1990 Jun 12;29(23):5491-9
(Latest) J:198191 Li C, et al., Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling. Dev Biol. 2013 Jun 1;378(1):13-24
All references(46)
Other
accession IDs
MGD-MRK-2328, MGD-MRK-2329

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory