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Cyp2b10
Gene Detail
Symbol

Name
ID
Cyp2b10
cytochrome P450, family 2, subfamily b, polypeptide 10
MGI:88598
Synonyms
Cyp2b, Cyp2b20, p16, phenobarbitol inducible, type b
Feature Type
protein coding gene
Genetic Map
Chromosome 7
14.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr7:25897620-25926624 bp, + strand
From VEGA annotation of GRCm38

  29005 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:73894  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2b10

Human
homologs
Human Homolog CYP2B6, cytochrome P450, family 2, subfamily B, polypeptide 6
NCBI Gene ID 1555
neXtProt AC  NX_P20813
Human Synonyms  CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450
Human Chr (Location)  19q13.2; chr19:40991243-41018398 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP2B6
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Genomic Mutations involving Cyp2b10 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp2b10 interacts with 99 markers (Mir1b, Mir27a, Mir27b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process cellular ketone metabolic process, drug metabolic process, ...
Component cytoplasm, endoplasmic reticulum, ...
Function arachidonic acid epoxygenase activity, aromatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (106)    Tissues (106)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
RT-PCR 12
cDNA source data(15)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(25) Genomic(3) cDNA(21) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000027165 (Evidence)
Ensembl Gene ModelENSMUSG00000030483 (Evidence)
Entrez Gene13088 (Evidence)
UniGene218749
DFCITC1585871
NIA Mouse Gene IndexU007829
EC1.14.14.1
Consensus CDS ProjectCCDS20999.1
International Mouse Knockout Project StatusCyp2b10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027165 VEGA Gene Model | MGI Sequence Detail 29005 C57BL/6J ±  kb
transcript OTTMUST00000067193 VEGA | MGI Sequence Detail 1822 Not Applicable 
polypeptide OTTMUSP00000033773 VEGA | MGI Sequence Detail 500 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(5)
Polymorphisms
RFLP(2) : SNPs within 2kb(354 from dbSNP Build 137)    SNPs within 2kb including multiple locations(358)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008068 Cytochrome P450, E-class, group I, CYP2B-like
Protein Ontology PR:000006222 cytochrome P450 2B10
References
(Earliest) J:6425 Atlas SA, et al., Genetic differences in phenytoin pharmacokinetics. In vivo clearance and in vitro metabolism among inbred strains of mice. Dev Pharmacol Ther. 1980;1(5):281-304
(Latest) J:213153 Harms MJ, et al., Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604
All references(60)
Other
accession IDs
MGD-MRK-2315, MGD-MRK-2316, MGI:1202389

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory