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Cyct Gene Detail
Summary
  • Symbol
    Cyct
  • Name
    cytochrome c, testis
  • Synonyms
    T-Cc
  • Feature Type
    protein coding gene
  • IDs
    MGI:88579
    NCBI Gene: 13067
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:76353942-76360450 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 44.94 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88579
protein coding gene Chr2:76353942-76360453 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025863
protein coding gene Chr2:76749560-76757763 (-)
A/J MGP_AJ_G0025840
protein coding gene Chr2:73763707-73770281 (-)
AKR/J MGP_AKRJ_G0025809
protein coding gene Chr2:75745594-75752090 (-)
BALB/cJ MGP_BALBcJ_G0025835
protein coding gene Chr2:73942932-73949525 (-)
C3H/HeJ MGP_C3HHeJ_G0025595
protein coding gene Chr2:75960280-75966849 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026282
protein coding gene Chr2:79023229-79029730 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023685
protein coding gene Chr2:71168586-71175206 (-)
CAST/EiJ MGP_CASTEiJ_G0025057
protein coding gene Chr2:76288404-76294929 (-)
CBA/J MGP_CBAJ_G0025576
protein coding gene Chr2:81950490-81957069 (-)
DBA/2J MGP_DBA2J_G0025707
protein coding gene Chr2:73355352-73361957 (-)
FVB/NJ MGP_FVBNJ_G0025669
protein coding gene Chr2:72725278-72734372 (-)
LP/J MGP_LPJ_G0025795
protein coding gene Chr2:76630202-76636811 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025700
protein coding gene Chr2:83784922-83791081 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026338
protein coding gene Chr2:75871727-75878297 (-)
PWK/PhJ MGP_PWKPhJ_G0024800
protein coding gene Chr2:73311943-73318836 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024606
protein coding gene Chr2:76112334-76120665 (-)
WSB/EiJ MGP_WSBEiJ_G0025126
protein coding gene Chr2:76330758-76338046 (-)



Homology
more
  • Human Ortholog
    CYCTP, cytochrome c, testis, pseudogene
  • Vertebrate Orthologs
    4
  • Human Ortholog
    CYCTP, cytochrome c, testis, pseudogene
    Orthology source: HGNC
  • Synonyms
    HCP9
  • Links
    NCBI Gene ID: 360163

  • Chr Location
    2q31.2; chr2:178092500-178104470 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation exhibit reduced sperm counts, impaired fertilization and testicular atrophy due to a dysfunction of oxidative phosphorylation in the spermatocytes.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056436 Ensembl Gene Model | MGI Sequence Detail 6509 C57BL/6J ±  kb
transcript ENSMUST00000028430 Ensembl | MGI Sequence Detail 655 Not Applicable  
polypeptide ENSMUSP00000028430 Ensembl | MGI Sequence Detail 105 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 2
    cDNA 14
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-2288
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:9150 Virbasius JV, et al., Structure and expression of rodent genes encoding the testis-specific cytochrome c. Differences in gene structure and evolution between somatic and testicular variants. J Biol Chem. 1988 May 15;263(14):6791-6
  • Latest
    J:271018 Auclair G, et al., EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos. Genome Res. 2016 Feb;26(2):192-202

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory