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Cyct
Gene Detail
Symbol

Name
ID
Cyct
cytochrome c, testis
MGI:88579
Synonyms
T-Cc
Feature Type
protein coding gene
Genetic Map
Chromosome 2
44.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr2:76353942-76360450 bp, - strand
From VEGA annotation of GRCm38

  6509 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129551  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 cattle

HCOP human homology predictions: CYCTP
Gene Tree: Cyct

Human
homologs
CYCTP, cytochrome c, testis, pseudogene
Orthology source: HGNC

IDs:
NCBI Gene ID: 360163

Human Synonyms: HCP9

Human Chr (Location): 2q31.2; chr2:178092500-178104470 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Genomic Mutations involving Cyct (2)
 
Mice homozygous for a targeted null mutation exhibit reduced sperm counts, impaired fertilization and testicular atrophy due to a dysfunction of oxidative phosphorylation in the spermatocytes.
 
Interactions
Cyct interacts with 19 markers (Mir7-2, Mir7b, Mir96, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process apoptotic process, ATP synthesis coupled electron transport, ...
Component mitochondrial intermembrane space, mitochondrion, ...
Function electron carrier activity, heme binding, ...
External Resources: FuncBase
Expression
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cyct    NEW 
Molecular
reagents
All nucleic(16) Genomic(2) cDNA(13) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000013135 (Evidence)
Ensembl Gene Model ENSMUSG00000056436 (Evidence)
Entrez Gene 13067 (Evidence)
UniGene 4872
DFCI TC1586116
DoTS DT.60117837
NIA Mouse Gene Index U157853
PDB 2AIU
Consensus CDS Project CCDS16156.1
International Mouse Phenotyping Consortium Status Cyct
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013135 VEGA Gene Model | MGI Sequence Detail 6509 C57BL/6J ±  kb
transcript OTTMUST00000031706 VEGA | MGI Sequence Detail 655 Not Applicable 
polypeptide OTTMUSP00000014130 VEGA | MGI Sequence Detail 105 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(4) UniProt(2)
Polymorphisms
RFLP(2) : SNPs within 2kb(91 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002327 Cytochrome c, class IA/ IB
InterPro IPR009056 Cytochrome c domain
Protein Ontology PR:000002322 cytochrome c, testis-specific
References
(Earliest) J:9150 Virbasius JV, et al., Structure and expression of rodent genes encoding the testis-specific cytochrome c. Differences in gene structure and evolution between somatic and testicular variants. J Biol Chem. 1988 May 15;263(14):6791-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGD-MRK-2288

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory