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Cycs
Gene Detail
Symbol

Name
ID
Cycs
cytochrome c, somatic
MGI:88578
Feature Type
protein coding gene
Genetic Map
Chromosome 6
24.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr6:50562563-50566538 bp, - strand
From VEGA annotation of GRCm38

  3976 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133055  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: CYCS
Gene Tree: Cycs

Human
homologs
CYCS, cytochrome c, somatic
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 54205
neXtProt AC: NX_P99999

Human Synonyms: CYC, HCS, THC4

Human Chr (Location): 7p15.3; chr7:25118651-25125361 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CYCS

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(3) Targeted(5) Transgenic(2)
Incidental mutations (data from APF )
 
Mice homozygous for a targeted mutation die at midgestation. By E8.5, homozygous null embryos exhibit a strikingly reduced size and are developmentally retarded.
 
Interactions
Cycs interacts with 295 markers (Mir1b, Mir7-1, Mir7-2, ...)
Expression
Literature Summary: (11 records)
Data Summary: Results (167)    Tissues (45)    Images (29)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 150
Western blot 8
RT-PCR 9
cDNA source data(229)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cycs    NEW 
Molecular
reagents
All nucleic(232) Genomic(2) cDNA(229) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000034264 (Evidence)
Ensembl Gene Model ENSMUSG00000063694 (Evidence)
Entrez Gene 13063 (Evidence)
UniGene 35389
DFCI TC1573177, TC1669169
DoTS DT.101277138, DT.102540369, DT.496226
NIA Mouse Gene Index U019315, U047743, U060791, U069135, U093555
Consensus CDS Project CCDS20131.1
International Mouse Phenotyping Consortium Status Cycs
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034264 VEGA Gene Model | MGI Sequence Detail 3976 C57BL/6J ±  kb
transcript OTTMUST00000087067 VEGA | MGI Sequence Detail 3123 Not Applicable 
polypeptide OTTMUSP00000047209 VEGA | MGI Sequence Detail 105 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2)
Polymorphisms
RFLP(2) : SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000002321 cytochrome c, somatic
References
(Earliest) J:38101 Limbach KJ, et al., Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes. Nucleic Acids Res. 1985 Jan 25;13(2):617-30
(Latest) J:213153 Harms MJ, et al., Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604
All references(69)
Other
accession IDs
MGD-MRK-2287

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory