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Ctla2b Gene Detail
Summary
  • Symbol
    Ctla2b
  • Name
    cytotoxic T lymphocyte-associated protein 2 beta
  • Synonyms
    Ctla-2b
  • Feature Type
    protein coding gene
  • IDs
    MGI:88555
    NCBI Gene: 13025
  • Member of
    Ctla2 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:61043164-61045261 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 32.53 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88555
 protein coding gene Chr13:61043164-61045269 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020652
 protein coding gene Chr13:60672312-60674379 (-)
A/J MGP_AJ_G0020607
 protein coding gene Chr13:58388834-58391309 (-)
AKR/J MGP_AKRJ_G0020583
 protein coding gene Chr13:60121350-60123395 (-)
BALB/cJ MGP_BALBcJ_G0020603
 protein coding gene Chr13:58648803-58654108 (-)
C3H/HeJ MGP_C3HHeJ_G0020400
 protein coding gene Chr13:59926894-59930347 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021037
 protein coding gene Chr13:62481033-62483117 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018619
 protein coding gene Chr13:56252501-56254448 (-)
CAST/EiJ MGP_CASTEiJ_G0019916
 protein coding gene Chr13:60155630-60196487 (-)
CBA/J MGP_CBAJ_G0020360
 protein coding gene Chr13:64825131-64827222 (-)
DBA/2J MGP_DBA2J_G0020484
 protein coding gene Chr13:57922914-57924933 (-)
FVB/NJ MGP_FVBNJ_G0020462
 protein coding gene Chr13:57424013-57425848 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0020492
 protein coding gene Chr13:64096302-64099639 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021080
 protein coding gene Chr13:59737687-59740115 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019500
 protein coding gene Chr13:58698471-58700280 (-)
WSB/EiJ MGP_WSBEiJ_G0019978
 protein coding gene Chr13:60193499-60195532 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    27
  • cDNA Data
    29
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074874 Ensembl Gene Model | MGI Sequence Detail 2098 C57BL/6J ±  kb
transcript ENSMUST00000021884 Ensembl | MGI Sequence Detail 842 Not Applicable  
polypeptide ENSMUSP00000021884 Ensembl | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 30

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-2222, MGD-MRK-2232, MGI:2145446
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:246986 Silva-Vilches C, et al., Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion. PLoS One. 2017;12(7):e0178114
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory