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Ctla2a Gene Detail
Summary
  • Symbol
    Ctla2a
  • Name
    cytotoxic T lymphocyte-associated protein 2 alpha
  • Synonyms
    Ctla-2a
  • Feature Type
    protein coding gene
  • IDs
    MGI:88554
    NCBI Gene: 13024
  • Member of
    Ctla2 cluster
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:60934155-60936625 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 32.56 cM, cytoband B-C1
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    16
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88554
protein coding gene Chr13:60934155-60936625 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020654
protein coding gene Chr13:60715161-60717631 (-)
A/J MGP_AJ_G0020609
protein coding gene Chr13:58427503-58429973 (-)
AKR/J MGP_AKRJ_G0020584
protein coding gene Chr13:60160435-60162905 (-)
BALB/cJ MGP_BALBcJ_G0020605
protein coding gene Chr13:58690662-58693132 (-)
C3H/HeJ MGP_C3HHeJ_G0020402
protein coding gene Chr13:59965531-59968001 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021039
protein coding gene Chr13:62519826-62522296 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018620
protein coding gene Chr13:56252602-56254470 (-)
CAST/EiJ MGP_CASTEiJ_G0019918
protein coding gene Chr13:60194238-60196509 (-)
CBA/J MGP_CBAJ_G0020362
protein coding gene Chr13:64868624-64871094 (-)
DBA/2J MGP_DBA2J_G0020486
protein coding gene Chr13:57965503-57967973 (-)
FVB/NJ MGP_FVBNJ_G0020464
protein coding gene Chr13:57465229-57467909 (-)
LP/J MGP_LPJ_G0020562
protein coding gene Chr13:60962467-60967177 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020494
protein coding gene Chr13:64137213-64139706 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021082
protein coding gene Chr13:59778312-59780782 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019498
protein coding gene Chr13:58664156-58666020 (-)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13024 NCBI Gene Model | MGI Sequence Detail 2471 C57BL/6J ±  kb
transcript NM_007796 RefSeq | MGI Sequence Detail 1373 C57BL/6  
polypeptide P12399 UniProt | EBI | MGI Sequence Detail 137 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 140
    Genomic 1
    cDNA 138
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-2221, MGD-MRK-2231
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:246986 Silva-Vilches C, et al., Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion. PLoS One. 2017;12(7):e0178114

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory