About   Help   FAQ
Csnk2b
Gene Detail
 Symbol
Name
ID
Csnk2b
casein kinase 2, beta polypeptide
MGI:88548
Feature Type protein coding gene
Genetic Map
Chromosome 17
18.59 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:35116196-35122053 bp, - strand
From VEGA annotation of GRCm38

  5858 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55572  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: human casein kinase II beta chain
Gene Tree: Csnk2b

Human
homologs
Human Homolog CSNK2B, casein kinase 2, beta polypeptide
NCBI Gene ID 1460
neXtProt AC  NX_P67870
Human Synonyms  CK2B, CK2N, CSK2B, G5A
Human Chr (Location)  6p21.3; chr6:31665880-31670070 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(11) Targeted(4)
 
Mice homozygous for a targeted mutation exhibit embryonic lethality post-implantation, growth retardation and arrest, a failure to form an inner cell mass and smaller size.
 
Interactions
Csnk2b interacts with 6 markers (Mir32, Mir140, Mir205, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process adiponectin-activated signaling pathway, endothelial tube morphogenesis, ...
Component cytoplasm, extracellular vesicular exosome, ...
Function identical protein binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (100)    Tissues (70)    Images (3)
Theiler Stages: 17, 19, 20, 23, 24, 26
Assay TypeResults
Immunohistochemistry 29
RNA in situ 71
cDNA source data(195)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(205) Genomic(9) cDNA(195) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037175 (Evidence)
Ensembl Gene ModelENSMUSG00000024387 (Evidence)
Entrez Gene13001 (Evidence)
UniGene378901
DFCITC1572255
DoTSDT.101738730, DT.110551298, DT.495510
NIA Mouse Gene IndexU037738
Consensus CDS ProjectCCDS28684.1
International Mouse Knockout Project StatusCsnk2b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037175 VEGA Gene Model | MGI Sequence Detail 5858 C57BL/6J ±  kb
transcript OTTMUST00000095775 VEGA | MGI Sequence Detail 883 Not Applicable 
polypeptide OTTMUSP00000053462 VEGA | MGI Sequence Detail 257 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(18) UniProt(11)
Polymorphisms SNPs within 2kb(68 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000704 Casein kinase II, regulatory subunit
InterPro IPR016149 Casein kinase II, regulatory subunit, alpha-helical
InterPro IPR016150 Casein kinase II, regulatory subunit, beta-sheet
Protein Ontology PR:000005952 casein kinase II subunit beta
References (Earliest) J:10587 Kopatz I, et al., The nucleotide sequence of the mouse cDNA encoding the beta subunit of casein kinase II. Nucleic Acids Res. 1990 Jun 25;18(12):3639
(Latest) J:190725 Iyengar AS, et al., Identification of CK2 as the kinase that phosphorylates Pax3 at Ser209 in early myogenic differentiation. Biochem Biophys Res Commun. 2012 Nov 9;428(1):24-30
All references(52)
Other
accession IDs
MGD-MRK-2206

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory