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Csnk2a1
Gene Detail
Symbol

Name
ID
Csnk2a1
casein kinase 2, alpha 1 polypeptide
MGI:88543
Synonyms
Csnk2a1-rs4
Feature Type
protein coding gene
Genetic Map
Chromosome 2
74.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:152226839-152281852 bp, + strand
From VEGA annotation of GRCm38

  55014 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:90874  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CSNK2A1
Protein SuperFamily: kinase-related transforming protein
Gene Tree: Csnk2a1

Human
homologs
CSNK2A1, casein kinase 2, alpha 1 polypeptide
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1457
neXtProt AC: NX_P68400

Human Synonyms: CK2A1, CKII, CSNK2A3

Human Chr (Location): 20p13; chr20:472969-543838 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(85) : Gene trapped(81) Targeted(4)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for the null in the major catalytic subunit die by E11.5 and exhibit defects in neural, cardiac and limb development.
 
Interactions
Csnk2a1 interacts with 378 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (13 records)
Data Summary: Results (313)    Tissues (240)    Images (33)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 37
RNA in situ 230
RT-PCR 46
cDNA source data(117)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100498392 ; ZFIN csnk2a1    NEW 
Molecular
reagents
All nucleic(124) Genomic(3) cDNA(119) Primer pair(2)
Microarray probesets(11)
Other database
links
VEGA Gene Model OTTMUSG00000015858 (Evidence)
Ensembl Gene Model ENSMUSG00000074698 (Evidence)
Entrez Gene 12995 (Evidence)
UniGene 23692
DFCI TC1574149, TC1589511, TC1658918, TC1674920, TC1687972
DoTS DT.101186575, DT.101312944, DT.101380074, DT.531953, DT.533604, DT.94290322
NIA Mouse Gene Index U000951, U042384
Consensus CDS Project CCDS16879.1
International Mouse Phenotyping Consortium Status Csnk2a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015858 VEGA Gene Model | MGI Sequence Detail 55014 C57BL/6J ±  kb
transcript OTTMUST00000037681 VEGA | MGI Sequence Detail 4206 Not Applicable 
polypeptide OTTMUSP00000016898 VEGA | MGI Sequence Detail 391 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(6)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000005950 casein kinase II subunit alpha
References
(Earliest) J:2617 Yang-Feng TL, et al., Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit. Nucleic Acids Res. 1991 Dec;19(25):7125-9
(Latest) J:203719 Umemura Y, et al., An in vitro ES cell-based clock recapitulation assay model identifies CK2alpha as an endogenous clock regulator. PLoS One. 2013;8(6):e67241
All references(62)
Other
accession IDs
MGD-MRK-2201, MGI:894650

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory