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Csn2 Gene Detail
Summary
  • Symbol
    Csn2
  • Name
    casein beta
  • Synonyms
    CSN2, Csnb
Location &
Maps
more
  • Sequence Map
    Chr5:87840478-87847288 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    20 experiments
Strain
Comparison
more
  • SNPs within 2kb
    318 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
  • RFLP
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88541
 protein coding gene Chr5:87840478-87847489 (-)
129S1/SvImJ ENSMUSG00200008868
 protein coding gene Chr5:83571818-83578816 (-)
A/J ENSMUSG00195024328
 protein coding gene Chr5:82742024-82749030 (-)
AKR/J ENSMUSG00220010851
 protein coding gene Chr5:82882117-82889123 (-)
BALB/cJ ENSMUSG00180024595
 protein coding gene Chr5:82574845-82581847 (-)
C3H/HeJ ENSMUSG00175039939
 protein coding gene Chr5:84650002-84657004 (-)
C57BL/6NJ ENSMUSG00215016812
 protein coding gene Chr5:83435064-83442070 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027359
 protein coding gene Chr5:80652992-80660188 (-)
CAST/EiJ ENSTCUG00005034096
 protein coding gene Chr5:82285509-82292488 (-)
CBA/J ENSMUSG00210005455
 protein coding gene Chr5:83465296-83472298 (-)
DBA/2J ENSMUSG00185036473
 protein coding gene Chr5:85384494-85391496 (-)
FVB/NJ ENSMUSG00205022171
 protein coding gene Chr5:82268943-82275949 (-)
JF1/MsJ ENSUMUG00000000794
 protein coding gene Chr5:89843860-89850863 (-)
LP/J ENSMUSG00230001260
 protein coding gene Chr5:90101821-90108819 (-)
NOD/ShiLtJ ENSMUSG00190032033
 protein coding gene Chr5:82326579-82333581 (-)
NZO/HlLtJ ENSMUSG00225008349
 protein coding gene Chr5:95130790-95137796 (-)
PWK/PhJ ENSLUMG00010025095
 protein coding gene Chr5:82344561-82351555 (-)
SPRET/EiJ ENSMSPG00010030087
 protein coding gene Chr5:84667570-84673373 (-)
WSB/EiJ ENSIUOG00005028114
 protein coding gene Chr5:85284156-85291162 (-)



Homology
more
  • Human Ortholog
    CSN2, casein beta
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSN2, casein beta
  • Synonyms
    CASB, PDC213
  • Links
    NCBI Gene ID: 1447
    UniProt: P05814

  • Chr Location
    4q13.3; chr4:69955256-69965728 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Female mice homozygous for disruption of this gene produce mile with a low protein content and poor nutritional value.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    667
  • Tissues
    47
  • cDNA Data
    2272
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12991 NCBI Gene Model | MGI Sequence Detail 6811 C57BL/6J ±  kb
    transcript NM_001286021 RefSeq | MGI Sequence Detail 1141 ZRU/MplStud  
    polypeptide P10598 UniProt | EBI | MGI Sequence Detail 231 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 2297
      Genomic 15
      cDNA 2275
      Primer pair 3
      Other 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-2199
    References
    more
    • Summaries
      All 85
      Developmental Gene Expression 11
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:381083 Hanin G, et al., ZFP57 is a regulator of postnatal growth and life-long health. Nat Commun. 2026 Jan 27;17(1)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory