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Csn1s1
Gene Detail
Symbol

Name
ID
Member of
Csn1s1
casein alpha s1
MGI:88540
Csn cluster
Synonyms
Csna
Feature Type
protein coding gene
Genetic Map
Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(14)
Sequence Map
Chr5:87666224-87682573 bp, + strand
From Ensembl annotation of GRCm38

  16350 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: alpha-s1-casein
Gene Tree: Csn1s1
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display reduced milk prodution and abnormal milk composition with reduced protein, calcium and phosphate concentrations.
 
Interactions
Csn1s1 interacts with 86 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process transport
Component extracellular region
Function transporter activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (46)    Tissues (45)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 46
cDNA source data(1899)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(1912) Genomic(7) cDNA(1902) Primer pair(1) Other(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000070702 (Evidence)
Entrez Gene12990 (Evidence)
UniGene427467
DFCITC1573689, TC1584562, TC1586482, TC1603086, TC1620908
DoTSDT.101363593, DT.101363818, DT.101363870, DT.101720726, DT.101720727, DT.101721108, DT.91385665, DT.91437906, DT.91591221, DT.97395553, DT.97395812
NIA Mouse Gene IndexU005741
Consensus CDS ProjectCCDS51534.1
International Mouse Knockout Project StatusCsn1s1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070702 Ensembl Gene Model | MGI Sequence Detail 16350 C57BL/6J ±  kb
transcript ENSMUST00000094641 Ensembl | MGI Sequence Detail 1415 Not Applicable 
polypeptide ENSMUSP00000092225 Ensembl | MGI Sequence Detail 313 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(6) UniProt(9)
Polymorphisms
RFLP(2) : SNPs within 2kb(156 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026999 Alpha-s1 casein
InterPro IPR001588 Casein, alpha/beta
Protein Ontology PR:000005940 alpha-S1-casein
References
(Earliest) J:6738 Gupta P, et al., Localization of the casein gene family to a single mouse chromosome. J Cell Biol. 1982 Apr;93(1):199-204
(Latest) J:174932 Kolb AF, et al., Milk Lacking alpha-Casein Leads to Permanent Reduction in Body Size in Mice. PLoS One. 2011;6(7):e21775
All references(43)
Other
accession IDs
MGD-MRK-2198, MGI:2140790, MGI:2141176

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory