About   Help   FAQ
Csn1s1
Gene Detail
Symbol

Name
ID
Member of
Csn1s1
casein alpha s1
MGI:88540
Csn cluster
Synonyms
Csna
Feature Type
protein coding gene
Genetic Map
Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(14)
Sequence Map
Chr5:87666208-87682578 bp, + strand
From VEGA annotation of GRCm38

  16371 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: alpha-s1-casein
Gene Tree: Csn1s1
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation display reduced milk prodution and abnormal milk composition with reduced protein, calcium and phosphate concentrations.
 
Interactions
Csn1s1 interacts with 86 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process transport
Component extracellular region
Function transporter activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (46)    Tissues (45)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 46
cDNA source data(1899)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(1912) Genomic(7) cDNA(1902) Primer pair(1) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000054070 (Evidence)
Ensembl Gene Model ENSMUSG00000070702 (Evidence)
Entrez Gene 12990 (Evidence)
UniGene 427467
DFCI TC1573689, TC1584562, TC1586482, TC1603086, TC1620908
DoTS DT.101363593, DT.101363818, DT.101363870, DT.101720726, DT.101720727, DT.101721108, DT.91385665, DT.91437906, DT.91591221, DT.97395553, DT.97395812
NIA Mouse Gene Index U005741
Consensus CDS Project CCDS51534.1, CCDS80314.1
International Mouse Phenotyping Consortium Status Csn1s1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000054070 VEGA Gene Model | MGI Sequence Detail 16371 C57BL/6J ±  kb
transcript OTTMUST00000134355 VEGA | MGI Sequence Detail 1411 Not Applicable 
polypeptide OTTMUSP00000071256 VEGA | MGI Sequence Detail 313 Not Applicable 

For the selected sequences
All sequences(70) RefSeq(6) UniProt(7)
Polymorphisms
RFLP(2) : SNPs within 2kb(156 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026999 Alpha-s1 casein
InterPro IPR001588 Casein, alpha/beta
Protein Ontology PR:000005940 alpha-S1-casein
References
(Earliest) J:6738 Gupta P, et al., Localization of the casein gene family to a single mouse chromosome. J Cell Biol. 1982 Apr;93(1):199-204
(Latest) J:174932 Kolb AF, et al., Milk Lacking alpha-Casein Leads to Permanent Reduction in Body Size in Mice. PLoS One. 2011;6(7):e21775
All references(40)
Other
accession IDs
MGD-MRK-2198, MGI:2140790, MGI:2141176

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory