Csn1s1
Gene Detail

Symbol

Name
ID
Member of

Csn1s1
casein alpha s1
MGI:88540
Csn cluster

Synonyms

Csna

Feature Type

protein coding gene

Genetic Map

Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(14)

Sequence Map

Chr5:87666224-87682573 bp, + strand From Ensembl annotation of GRCm38   16350 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

Protein SuperFamily: alpha-s1-casein
Gene Tree: Csn1s1

Mutations,
alleles, and
phenotypes

All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 

Mice homozygous for a null mutation display reduced milk prodution and abnormal milk composition with reduced protein, calcium and phosphate concentrations.

 

Interactions

Csn1s1 interacts with 86 markers (Mir7-1, Mir9-1, Mir9-2, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (3 annotations)

Process	transport
Component	extracellular region
Function	transporter activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (46)    Tissues (45)    Images (1)    Tissue x Stage Matrix (view)

Assay Type	Results
RT-PCR	46

cDNA source data(1899)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(1912) Genomic(7) cDNA(1902) Primer pair(1) Other(2)
Microarray probesets(3)

Other database
links

Ensembl Gene Model	ENSMUSG00000070702 (Evidence)
Entrez Gene	12990 (Evidence)
UniGene	427467
DFCI	TC1573689, TC1584562, TC1586482, TC1603086, TC1620908
DoTS	DT.101363593, DT.101363818, DT.101363870, DT.101720726, DT.101720727, DT.101721108, DT.91385665, DT.91437906, DT.91591221, DT.97395553, DT.97395812
NIA Mouse Gene Index	U005741
Consensus CDS Project	CCDS51534.1
International Mouse Knockout Project Status	Csn1s1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000070702	Ensembl Gene Model | MGI Sequence Detail	16350	C57BL/6J
transcript	ENSMUST00000094641	Ensembl | MGI Sequence Detail	1415	Not Applicable
polypeptide	ENSMUSP00000092225	Ensembl | MGI Sequence Detail	313	Not Applicable

All sequences(48) RefSeq(6) UniProt(5)

Polymorphisms

RFLP(2) : SNPs within 2kb(156 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR026999	Alpha-s1 casein
InterPro	IPR001588	Casein, alpha/beta
Protein Ontology	PR:000005940	alpha-S1-casein

References

(Earliest) J:6738 Gupta P, et al., Localization of the casein gene family to a single mouse chromosome. J Cell Biol. 1982 Apr;93(1):199-204
(Latest) J:174932 Kolb AF, et al., Milk Lacking alpha-Casein Leads to Permanent Reduction in Body Size in Mice. PLoS One. 2011;6(7):e21775
All references(43)

Other
accession IDs

MGD-MRK-2198, MGI:2140790, MGI:2141176