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Crygf
Gene Detail
Symbol

Name
ID
Member of
Crygf
crystallin, gamma F
MGI:88526
Cryg cluster
Synonyms
3110001K11Rik, Cryg-2, DGcry-2, Len-2
Feature Type
protein coding gene
Genetic Map
Chromosome 1
33.31 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(14)
Sequence Map
Chr1:65926520-65928307 bp, + strand
From VEGA annotation of GRCm38

  1788 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128417  Vertebrate Homology Class
2 mouse; 1 rat; 1 rhesus macaque; 2 cattle; 2 dog; 2 zebrafish

Protein SuperFamily: beta/gamma crystallins
Gene Tree: Crygf

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Chemically induced (other)(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a chemically-induced single point mutation exhibit homogeneous cataracts while heterozygotes display less severe rays and concentric circles of lens opacity.
 
Interactions
Crygf interacts with 32 markers (Mir18b, Mir129-1, Mir129-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Process eye development
Function structural constituent of eye lens
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (43)    Tissues (8)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 15
RT-PCR 24
Nuclease S1 4
cDNA source data(86)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(95) Genomic(3) cDNA(87) Primer pair(4) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024984 (Evidence)
Ensembl Gene ModelENSMUSG00000025945 (Evidence)
Entrez Gene12969 (Evidence)
UniGene275362
DoTSDT.99863390
Consensus CDS ProjectCCDS15018.1
International Mouse Knockout Project StatusCrygf
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024984 VEGA Gene Model | MGI Sequence Detail 1788 C57BL/6J ±  kb
transcript OTTMUST00000061489 VEGA | MGI Sequence Detail 627 Not Applicable 
polypeptide OTTMUSP00000030171 VEGA | MGI Sequence Detail 174 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(3) : SNPs within 2kb(76 from dbSNP Build 137)    SNPs within 2kb including multiple locations(78)
Protein-related
information
ResourceIDDescription
InterPro IPR001064 Beta/gamma crystallin
InterPro IPR011024 Gamma-crystallin-related
Protein Ontology PR:000006202 gamma-crystallin F
References
(Earliest) J:8369 Lok S, et al., Lens-specific promoter activity of a mouse gamma-crystallin gene. Mol Cell Biol. 1985 Sep;5(9):2221-30
(Latest) J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71
All references(56)
Other
accession IDs
MGD-MRK-2171, MGD-MRK-2181, MGD-MRK-8837, MGI:1916514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory