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Cryge Gene Detail
Summary
  • Symbol
    Cryge
  • Name
    crystallin, gamma E
  • Synonyms
    Cryg-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:88525
    NCBI Gene: 12968
  • Member of
    Cryg cluster
Location & Maps
more
  • Sequence Map
    Chr1:65048554-65051149 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2596 bp   ±  kb flank

  • Genome Browsers
Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 10 alleles in 10 genetic backgrounds
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    36
  • Chemically induced (ENU)
    4
  • Chemically induced (other)
    1
  • Gene trapped
    21
  • Radiation induced
    3
  • Spontaneous
    4
  • Targeted
    3
  • Genomic Mutations
    2 involving Cryge
  • Incidental Mutations
Mutations in this gene produce severe, nuclear and zonular cataracts with microphthalmia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021574 VEGA Gene Model | MGI Sequence Detail 2596 C57BL/6J ±  kb
transcript OTTMUST00000051206 VEGA | MGI Sequence Detail 631 Not Applicable  
polypeptide OTTMUSP00000024043 VEGA | MGI Sequence Detail 174 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    82 from dbSNP Build 142
  • PCR
  • RFLP
Protein
Information
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Molecular
Reagents
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  • All nucleic 205
    Genomic 2
    cDNA 200
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-2175, MGD-MRK-2180
References
more
  • Summaries
    All 67
    Developmental Gene Expression 12
    Gene Ontology 3
    Phenotypes 32
  • Earliest
    J:6481 Oda S, et al., Impaired development of lens fibers in genetic microphthalmia, eye lens obsolescence, Elo, of the mouse. Exp Eye Res. 1980 Dec;31(6):673-81
  • Latest
    J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory