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Cryga
Gene Detail
 Symbol
Name
ID
Member of
Cryga
crystallin, gamma A
MGI:88521
Cryg cluster
Synonyms Cryg-4, DGcry-4
Feature Type protein coding gene
Genetic Map
Chromosome 1
32.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr1:65100389-65103373 bp, - strand
From VEGA annotation of GRCm38

  2985 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129704  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: beta/gamma crystallins
Gene Tree: Cryga

Human
homologs
Human Homolog CRYGA, crystallin, gamma A
NCBI Gene ID 1418
neXtProt AC  NX_P11844
Human Synonyms  CRYG1, CRYG5, CRY-g-A
Human Chr (Location)  2q34; chr2:208160740-208163642 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Chemically induced (ENU)(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Heterozygotes for an ethylnitrosourea-induced replacement mutation exhibit a diffuse nuclear opacity of the lens.
 
Interactions
Cryga interacts with 22 markers (Mir25, Mir32, Mir92-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process eye development, lens development in camera-type eye
Function structural constituent of eye lens
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (20 records)
Data Summary: Results (38)    Tissues (15)    Images (7)
Theiler Stages: 16, 19, 20, 21, 22, 23, 24, 27, 28
Assay TypeResults
Immunohistochemistry 5
RNA in situ 1
Northern blot 15
RT-PCR 17
cDNA source data(310)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(315) Genomic(1) cDNA(311) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022111 (Evidence)
Ensembl Gene ModelENSMUSG00000044429 (Evidence)
Entrez Gene12964 (Evidence)
UniGene26904
DFCITC1572285
DoTSDT.99858796
NIA Mouse Gene IndexU268958
Consensus CDS ProjectCCDS15014.1
International Mouse Knockout Project StatusCryga
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022111 VEGA Gene Model | MGI Sequence Detail 2985 C57BL/6J ±  kb
transcript OTTMUST00000052487 VEGA | MGI Sequence Detail 625 Not Applicable 
polypeptide OTTMUSP00000024895 VEGA | MGI Sequence Detail 174 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms RFLP(2) : SNPs within 2kb(60 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001064 Beta/gamma crystallin
InterPro IPR011024 Gamma-crystallin-related
Protein Ontology PR:000005914 gamma-crystallin A
References (Earliest) J:6796 Shinohara T, et al., Multiple gamma-crystallins of the mouse lens: fractionation of mRNAs by cDNA cloning. Proc Natl Acad Sci U S A. 1982 May;79(9):2783-7
(Latest) J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71
All references(58)
Other
accession IDs
MGD-MRK-2173, MGD-MRK-2176, MGD-MRK-8839

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory