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Crabp1 Gene Detail
Summary
  • Symbol
    Crabp1
  • Name
    cellular retinoic acid binding protein I
  • Synonyms
    Crabp-1, CrabpI, Rbp-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:88490
    NCBI Gene: 12903
  • Gene Overview
    MyGene.info: CRABP1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54764748-54773110 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 29.76 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    118 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88490
protein coding gene Chr9:54764748-54773110 (.)
129S1/SvImJ MGP_129S1SvImJ_G0034830
protein coding gene Chr9:53826756-53835254 (+)
A/J MGP_AJ_G0034811
protein coding gene Chr9:52102738-52111093 (+)
AKR/J MGP_AKRJ_G0034740
protein coding gene Chr9:53285997-53296961 (+)
BALB/cJ MGP_BALBcJ_G0034803
protein coding gene Chr9:51877249-51885598 (+)
C3H/HeJ MGP_C3HHeJ_G0034513
protein coding gene Chr9:53749097-53758224 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035322
protein coding gene Chr9:55325722-55334084 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032234
protein coding gene Chr9:51521864-51530194 (+)
CAST/EiJ MGP_CASTEiJ_G0033835
protein coding gene Chr9:53776720-53786089 (+)
CBA/J MGP_CBAJ_G0034484
protein coding gene Chr9:57246507-57254840 (+)
DBA/2J MGP_DBA2J_G0034643
protein coding gene Chr9:51995524-52003913 (+)
FVB/NJ MGP_FVBNJ_G0034585
protein coding gene Chr9:51197138-51206143 (+)
LP/J MGP_LPJ_G0034726
protein coding gene Chr9:54139982-54150455 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034628
protein coding gene Chr9:58786299-58794666 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035344
protein coding gene Chr9:53297518-53305878 (+)
PWK/PhJ MGP_PWKPhJ_G0033539
protein coding gene Chr9:51978195-51986571 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033374
protein coding gene Chr9:53560541-53568828 (+)
WSB/EiJ MGP_WSBEiJ_G0033947
protein coding gene Chr9:53267286-53275625 (+)



Homology
more
  • Human Ortholog
    CRABP1, cellular retinoic acid binding protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRABP1, cellular retinoic acid binding protein 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CRABP, CRABPI, CRABP-I, RBP5
  • Links
    NCBI Gene ID: 1381
    neXtProt AC: NX_P29762
    UniProt: P29762

  • Chr Location
    15q25.1; chr15:78340324-78348230 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    11 phenotype references
Homozygotes for targeted null mutations are phenotypically normal and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 12903 NCBI Gene Model | MGI Sequence Detail 8363 C57BL/6J ±  kb
transcript NM_013496 RefSeq | MGI Sequence Detail 819 C57BL/6  
polypeptide P62965 UniProt | EBI | MGI Sequence Detail 137 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 91
    Genomic 8
    cDNA 55
    Primer pair 11
    Other 17

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13791, MGD-MRK-2126, MGD-MRK-2128, MGI:2143024
References
more
  • Summaries
    All 229
    Developmental Gene Expression 180
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:9912 Vaessen MJ, et al., Preferential expression of cellular retinoic acid binding protein in a subpopulation of neural cells in the developing mouse embryo. Differentiation. 1989 May;40(2):99-105
  • Latest
    J:257917 Magella B, et al., Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf. Dev Biol. 2018 Feb 1;434(1):36-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory