Crabp1 MGI Mouse Gene Detail - MGI:88490 - cellular retinoic acid binding protein I

Symbol

Crabp1
Name

cellular retinoic acid binding protein I
Synonyms

Crabp-1, CrabpI, Rbp-5

Feature Type

protein coding gene
IDs

MGI:88490
NCBI Gene: 12903
Alliance

genome feature page
Transcription Start Sites

11 TSS

Sequence Map

Chr9:54672032-54680394 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 29.76 cM
Mapping Data

10 experiments

SNPs within 2kb

317 from dbSNP Build 142
Strain Annotations

19
RFLP

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_88490	protein coding gene	Chr9:54672032-54680394 (+)
129S1/SvImJ	ENSMUSG00200035300	protein coding gene	Chr9:51799879-51808239 (+)
A/J	ENSMUSG00195039286	protein coding gene	Chr9:51497529-51505885 (+)
AKR/J	ENSMUSG00220030077	protein coding gene	Chr9:51630474-51638833 (+)
BALB/cJ	ENSMUSG00180017983	protein coding gene	Chr9:51610906-51619264 (+)
C3H/HeJ	ENSMUSG00175020311	protein coding gene	Chr9:51622721-51631076 (+)
C57BL/6NJ	ENSMUSG00215022553	protein coding gene	Chr9:51596064-51604428 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032234	protein coding gene	Chr9:51521864-51530194 (+)
CAST/EiJ	ENSTCUG00005019971	protein coding gene	Chr9:51532325-51540661 (+)
CBA/J	ENSMUSG00210032298	protein coding gene	Chr9:51726458-51734788 (+)
DBA/2J	ENSMUSG00185036632	protein coding gene	Chr9:51755811-51764168 (+)
FVB/NJ	ENSMUSG00205028727	protein coding gene	Chr9:52033411-52041776 (+)
JF1/MsJ	ENSUMUG00000038627	protein coding gene	Chr9:51765303-51773661 (+)
LP/J	ENSMUSG00230032338	protein coding gene	Chr9:51999855-52008215 (+)
NOD/ShiLtJ	ENSMUSG00190032038	protein coding gene	Chr9:51813098-51821462 (+)
NZO/HlLtJ	ENSMUSG00225027132	protein coding gene	Chr9:52020823-52029184 (+)
PWK/PhJ	ENSLUMG00010033282	protein coding gene	Chr9:51727654-51736026 (+)
SPRET/EiJ	ENSMSPG00010023902	protein coding gene	Chr9:52727891-52736169 (+)
WSB/EiJ	ENSIUOG00005035009	protein coding gene	Chr9:51224456-51232802 (+)

Human Ortholog

CRABP1, cellular retinoic acid binding protein 1

Vertebrate Orthologs

5

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CRABP1, cellular retinoic acid binding protein 1
Synonyms

CRABP, CRABP-I, CRABPI, RBP5
Links

HGNC:2338

NCBI Gene ID: 1381

UniProt: P29762
Chr Location

15q25.1; chr15:78340260-78348250 (+) GRCh38

MGI Vertebrate Homology

Crabp1 stringent orthology
1 human;1 mouse;1 rat;3 zebrafish
HCOP

vertebrate homology predictions: CRABP1
Gene Tree

Crabp1

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Phenotype Summary

5 phenotypes from 3 alleles in 3 genetic backgrounds
3 phenotypes from multigenic genotypes
23 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

19
Endonuclease-mediated

10
Gene trapped

3
Targeted

6
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

20 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Homozygotes for targeted null mutations are phenotypically normal and fertile.

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All GO Annotations

10
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

2009
Tissues

698
cDNA Data

52
Literature Summary

202

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas
Other Vertebrate Links

GEISHA CRABP1

Xenbase crabp1

ZFIN crabp1a, crabp1b, rbp5

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All Sequences

42
RefSeq

4
UniProt

2
CCDS

CCDS23195.1

Ensembl

ENSMUSG00000032291 (Evidence)
NCBI Gene

12903

			Length	Strain/Species	Flank
genomic	12903	NCBI Gene Model \| MGI Sequence Detail	8363	C57BL/6J	± kb
transcript	NM_013496	RefSeq \| MGI Sequence Detail	819	ZRU/MplStud
polypeptide	P62965	UniProt \| EBI \| MGI Sequence Detail	137	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000005843 cellular retinoic acid-binding protein 1

(term hierarchy)
PDB

1CBI, 1CBR
InterPro Domains

IPR012674 Calycin superfamily

IPR000463 Cytosolic fatty-acid binding

IPR031259 Intracellular lipid binding protein

IPR000566 Lipocalin/cytosolic fatty-acid binding domain

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All nucleic 105

Genomic 8

cDNA 56

Primer pair 15

Other 26

Antibodies 14

Microarray probesets 3

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MGD-MRK-13791, MGD-MRK-2126, MGD-MRK-2128, MGI:2143024

Summaries

All 265

Developmental Gene Expression 202

Gene Ontology 6

Phenotypes 23
Earliest

J:9912 Vaessen MJ, et al., Preferential expression of cellular retinoic acid binding protein in a subpopulation of neural cells in the developing mouse embryo. Differentiation. 1989 May;40(2):99-105
Latest

J:372750 Wang T, et al., Identification of a neural basis for energy expenditure in the mouse arcuate hypothalamus. Neuron. 2025 Sep 17;

TSS for Crabp1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr85172	Chr9:54671841-54671867 (+)	-178 bp
Tssr85173	Chr9:54672078-54672097 (+)	56 bp
Tssr85174	Chr9:54672836-54672848 (+)	810 bp
Tssr85175	Chr9:54672913-54672924 (+)	887 bp
Tssr85176	Chr9:54675725-54675735 (+)	3,698 bp
Tssr85177	Chr9:54680152-54680161 (+)	8,125 bp
Tssr85178	Chr9:54680163-54680170 (+)	8,135 bp
Tssr85179	Chr9:54680172-54680178 (+)	8,143 bp
Tssr85180	Chr9:54680193-54680201 (+)	8,165 bp
Tssr2876	Chr9:54680215-54680227 (+)	8,189 bp
Tssr85181	Chr9:54680237-54680252 (+)	8,213 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24