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Cox5b Gene Detail
Summary
  • Symbol
    Cox5b
  • Name
    cytochrome c oxidase subunit 5B
  • Feature Type
    protein coding gene
  • IDs
    MGI:88475
    NCBI Gene: 12859
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36730568-36732469 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 15.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    47 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88475
protein coding gene Chr1:36730530-36732762 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015930
protein coding gene Chr1:35242115-35246485 (+)
A/J MGP_AJ_G0015914
protein coding gene Chr1:34292485-34295264 (+)
AKR/J MGP_AKRJ_G0015869
protein coding gene Chr1:34771554-34773749 (+)
BALB/cJ MGP_BALBcJ_G0015868
protein coding gene Chr1:33980468-33983919 (+)
C3H/HeJ MGP_C3HHeJ_G0015701
protein coding gene Chr1:34978740-34980937 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016321
protein coding gene Chr1:36827769-36829966 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014043
protein coding gene Chr1:31345508-31347626 (+)
CAST/EiJ MGP_CASTEiJ_G0015282
protein coding gene Chr1:34859715-34861944 (+)
CBA/J MGP_CBAJ_G0015673
protein coding gene Chr1:37805598-37807794 (+)
DBA/2J MGP_DBA2J_G0015774
protein coding gene Chr1:33628161-33630472 (+)
FVB/NJ MGP_FVBNJ_G0015776
protein coding gene Chr1:33149633-33152527 (+)
LP/J MGP_LPJ_G0015844
protein coding gene Chr1:35611268-35613465 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015796
protein coding gene Chr1:40007692-40009889 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016368
protein coding gene Chr1:34816432-34820698 (+)
PWK/PhJ MGP_PWKPhJ_G0015065
protein coding gene Chr1:33381848-33385046 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014848
protein coding gene Chr1:34767902-34769739 (+)
WSB/EiJ MGP_WSBEiJ_G0015344
protein coding gene Chr1:34771588-34773784 (+)



Homology
more
  • Human Ortholog
    COX5B, cytochrome c oxidase subunit 5B
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX5B, cytochrome c oxidase subunit 5B
  • Synonyms
    COXVB
  • Links
    NCBI Gene ID: 1329
    neXtProt AC: NX_P10606
    UniProt: P10606

  • Chr Location
    2q11.2; chr2:97646062-97648383 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12859 NCBI Gene Model | MGI Sequence Detail 1902 C57BL/6J ±  kb
    transcript NM_009942 RefSeq | MGI Sequence Detail 584 C57BL/6  
    polypeptide P19536 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      Genomic 5
      cDNA 6
      Primer pair 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-2099
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 12
      Gene Ontology 8
      Phenotypes 11
    • Earliest
      J:10015 Nielsen PJ, et al., Nucleotide sequence of cDNA encoding mouse cytochrome c oxidase subunit Va. Nucleic Acids Res. 1989 Aug 25;17(16):6723
    • Latest
      J:294983 Yao Y, et al., Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis. Nat Commun. 2020 Jul 30;11(1):3822

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory