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Cox5b Gene Detail
Summary
  • Symbol
    Cox5b
  • Name
    cytochrome c oxidase subunit Vb
  • Feature Type
    protein coding gene
  • IDs
    MGI:88475
    NCBI Gene: 12859
  • Gene Overview
    MyGene.info: COX5B
Location & Maps
more
  • Sequence Map
    Chr1:36691484-36693681 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2198 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    COX5B, cytochrome c oxidase subunit 5B
  • Vertebrate Orthologs
    4
  • Human Ortholog
    COX5B, cytochrome c oxidase subunit 5B
    Orthology source: HGNC
  • Synonyms
    COXVB
  • Links
    NCBI Gene ID: 1329
    neXtProt AC: NX_P10606

  • Chr Location
    2q11.2; chr2:97646058-97648194 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    4
  • Genomic Mutations
    1 involving Cox5b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049480 VEGA Gene Model | MGI Sequence Detail 2198 C57BL/6J ±  kb
transcript OTTMUST00000126138 VEGA | MGI Sequence Detail 865 Not Applicable  
polypeptide OTTMUSP00000068266 VEGA | MGI Sequence Detail 129 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    48 from dbSNP Build 142
Protein
Information
less
  • Protein Ontology
    PR:000005780 cytochrome c oxidase subunit 5B, mitochondrial
Molecular
Reagents
less
  • All nucleic 11
    Genomic 4
    cDNA 6
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-2099
References
more
  • Summaries
    All 39
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:10015 Nielsen PJ, et al., Nucleotide sequence of cDNA encoding mouse cytochrome c oxidase subunit Va. Nucleic Acids Res. 1989 Aug 25;17(16):6723
  • Latest
    J:213153 Harms MJ, et al., Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory